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RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA.
Christensen SK, Gerdes K. Christensen SK, et al. Among authors: gerdes k. Mol Microbiol. 2003 Jun;48(5):1389-400. doi: 10.1046/j.1365-2958.2003.03512.x. Mol Microbiol. 2003. PMID: 12787364
Mechanism of post-segregational killing by the hok/sok system of plasmid R1. Sok antisense RNA regulates hok gene expression indirectly through the overlapping mok gene.
Thisted T, Gerdes K. Thisted T, et al. Among authors: gerdes k. J Mol Biol. 1992 Jan 5;223(1):41-54. doi: 10.1016/0022-2836(92)90714-u. J Mol Biol. 1992. PMID: 1370544
Mechanism of killer gene activation. Antisense RNA-dependent RNase III cleavage ensures rapid turn-over of the stable hok, srnB and pndA effector messenger RNAs.
Gerdes K, Nielsen A, Thorsted P, Wagner EG. Gerdes K, et al. J Mol Biol. 1992 Aug 5;226(3):637-49. doi: 10.1016/0022-2836(92)90621-p. J Mol Biol. 1992. PMID: 1380562
Mechanism of post-segregational killing by the hok/sok system of plasmid R1: sok antisense RNA regulates formation of a hok mRNA species correlated with killing of plasmid-free cells.
Gerdes K, Thisted T, Martinussen J. Gerdes K, et al. Mol Microbiol. 1990 Nov;4(11):1807-18. doi: 10.1111/j.1365-2958.1990.tb02029.x. Mol Microbiol. 1990. PMID: 1707122
The rifampicin-inducible genes srnB from F and pnd from R483 are regulated by antisense RNAs and mediate plasmid maintenance by killing of plasmid-free segregants.
Nielsen AK, Thorsted P, Thisted T, Wagner EG, Gerdes K. Nielsen AK, et al. Among authors: gerdes k. Mol Microbiol. 1991 Aug;5(8):1961-73. doi: 10.1111/j.1365-2958.1991.tb00818.x. Mol Microbiol. 1991. PMID: 1722558
The kis and kid genes of the parD maintenance system of plasmid R1 form an operon that is autoregulated at the level of transcription by the co-ordinated action of the Kis and Kid proteins.
Ruiz-Echevarría MJ, Berzal-Herranz A, Gerdes K, Díaz-Orejas R. Ruiz-Echevarría MJ, et al. Among authors: gerdes k. Mol Microbiol. 1991 Nov;5(11):2685-93. doi: 10.1111/j.1365-2958.1991.tb01977.x. Mol Microbiol. 1991. PMID: 1779758
The hok killer gene family in gram-negative bacteria.
Gerdes K, Poulsen LK, Thisted T, Nielsen AK, Martinussen J, Andreasen PH. Gerdes K, et al. New Biol. 1990 Nov;2(11):946-56. New Biol. 1990. PMID: 2101633 Review.
Translational control and differential RNA decay are key elements regulating postsegregational expression of the killer protein encoded by the parB locus of plasmid R1.
Gerdes K, Helin K, Christensen OW, Løbner-Olesen A. Gerdes K, et al. J Mol Biol. 1988 Sep 5;203(1):119-29. doi: 10.1016/0022-2836(88)90096-4. J Mol Biol. 1988. PMID: 2460630
Genetic analysis of the parB+ locus of plasmid R1.
Rasmussen PB, Gerdes K, Molin S. Rasmussen PB, et al. Among authors: gerdes k. Mol Gen Genet. 1987 Aug;209(1):122-8. doi: 10.1007/BF00329846. Mol Gen Genet. 1987. PMID: 3312951
Programmed cell death in bacteria: proteic plasmid stabilization systems.
Jensen RB, Gerdes K. Jensen RB, et al. Among authors: gerdes k. Mol Microbiol. 1995 Jul;17(2):205-10. doi: 10.1111/j.1365-2958.1995.mmi_17020205.x. Mol Microbiol. 1995. PMID: 7494469 Review.
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