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Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications.
Bourguet W, Germain P, Gronemeyer H. Bourguet W, et al. Among authors: germain p. Trends Pharmacol Sci. 2000 Oct;21(10):381-8. doi: 10.1016/s0165-6147(00)01548-0. Trends Pharmacol Sci. 2000. PMID: 11050318 Review.
Dimerization of nuclear receptors.
Germain P, Bourguet W. Germain P, et al. Methods Cell Biol. 2013;117:21-41. doi: 10.1016/B978-0-12-408143-7.00002-5. Methods Cell Biol. 2013. PMID: 24143970 Review.
Nuclear receptor ligand-binding domains: reduction of helix H12 dynamics to favour crystallization.
Nahoum V, Lipski A, Quillard F, Guichou JF, Boublik Y, Pérez E, Germain P, de Lera AR, Bourguet W. Nahoum V, et al. Among authors: germain p. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jul 1;64(Pt 7):614-6. doi: 10.1107/S1744309108015492. Epub 2008 Jun 11. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18607089 Free PMC article.
Structural and functional insights into the ligand-binding domain of a nonduplicated retinoid X nuclear receptor from the invertebrate chordate amphioxus.
Tocchini-Valentini GD, Rochel N, Escriva H, Germain P, Peluso-Iltis C, Paris M, Sanglier-Cianferani S, Van Dorsselaer A, Moras D, Laudet V. Tocchini-Valentini GD, et al. Among authors: germain p. J Biol Chem. 2009 Jan 16;284(3):1938-48. doi: 10.1074/jbc.M805692200. Epub 2008 Nov 4. J Biol Chem. 2009. PMID: 18986992
Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry.
Sanglier S, Bourguet W, Germain P, Chavant V, Moras D, Gronemeyer H, Potier N, Van Dorsselaer A. Sanglier S, et al. Among authors: germain p. Eur J Biochem. 2004 Dec;271(23-24):4958-67. doi: 10.1111/j.1432-1033.2004.04466.x. Eur J Biochem. 2004. PMID: 15606784
Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists.
Germain P, Gaudon C, Pogenberg V, Sanglier S, Van Dorsselaer A, Royer CA, Lazar MA, Bourguet W, Gronemeyer H. Germain P, et al. Chem Biol. 2009 May 29;16(5):479-89. doi: 10.1016/j.chembiol.2009.03.008. Chem Biol. 2009. PMID: 19477412
International Union of Pharmacology. LXIII. Retinoid X receptors.
Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. Germain P, et al. Pharmacol Rev. 2006 Dec;58(4):760-72. doi: 10.1124/pr.58.4.7. Pharmacol Rev. 2006. PMID: 17132853 Review.
Overview of nomenclature of nuclear receptors.
Germain P, Staels B, Dacquet C, Spedding M, Laudet V. Germain P, et al. Pharmacol Rev. 2006 Dec;58(4):685-704. doi: 10.1124/pr.58.4.2. Pharmacol Rev. 2006. PMID: 17132848 Review.
International Union of Pharmacology. LX. Retinoic acid receptors.
Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. Germain P, et al. Pharmacol Rev. 2006 Dec;58(4):712-25. doi: 10.1124/pr.58.4.4. Pharmacol Rev. 2006. PMID: 17132850 Review.
Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function.
Nahoum V, Pérez E, Germain P, Rodríguez-Barrios F, Manzo F, Kammerer S, Lemaire G, Hirsch O, Royer CA, Gronemeyer H, de Lera AR, Bourguet W. Nahoum V, et al. Among authors: germain p. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8. doi: 10.1073/pnas.0705356104. Epub 2007 Oct 18. Proc Natl Acad Sci U S A. 2007. PMID: 17947383 Free PMC article.
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