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Short stature and decreased insulin-like growth factor I (IGF-I)/growth hormone (GH)-ratio in an adult GH-deficient patient pointing to additional partial GH insensitivity due to a R179C mutation of the growth hormone receptor.
Meyer S, Ipek M, Keth A, Minnemann T, von Mach MA, Weise A, Ittner JR, Nawroth PP, Plöckinger U, Stalla GK, Tuschy U, Weber MM, Kann PH; German KIMS Board; German KIMS Pharmacogenetics Study Group. Meyer S, et al. Growth Horm IGF Res. 2007 Aug;17(4):307-14. doi: 10.1016/j.ghir.2007.03.001. Epub 2007 Apr 25. Growth Horm IGF Res. 2007. PMID: 17462934