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Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines.
Gerratana B. Gerratana B. Med Res Rev. 2012 Mar;32(2):254-93. doi: 10.1002/med.20212. Epub 2010 Jun 13. Med Res Rev. 2012. PMID: 20544978 Free PMC article. Review.
Identification of the dioxygenase-generated intermediate formed during biosynthesis of the dihydropyrrole moiety common to anthramycin and sibiromycin.
Saha S, Li W, Gerratana B, Rokita SE. Saha S, et al. Among authors: gerratana b. Bioorg Med Chem. 2015 Feb 1;23(3):449-54. doi: 10.1016/j.bmc.2014.12.024. Epub 2014 Dec 20. Bioorg Med Chem. 2015. PMID: 25564379 Free PMC article.
Biosynthesis of sibiromycin, a potent antitumor antibiotic.
Li W, Khullar A, Chou S, Sacramo A, Gerratana B. Li W, et al. Appl Environ Microbiol. 2009 May;75(9):2869-78. doi: 10.1128/AEM.02326-08. Epub 2009 Mar 6. Appl Environ Microbiol. 2009. PMID: 19270142 Free PMC article.
Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD+) synthetase inhibitors as potential antitubercular agents.
Wang X, Ahn YM, Lentscher AG, Lister JS, Brothers RC, Kneen MM, Gerratana B, Boshoff HI, Dowd CS. Wang X, et al. Among authors: gerratana b. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4426-4430. doi: 10.1016/j.bmcl.2017.08.012. Epub 2017 Aug 8. Bioorg Med Chem Lett. 2017. PMID: 28827112 Free PMC article.
Regulation of active site coupling in glutamine-dependent NAD(+) synthetase.
LaRonde-LeBlanc N, Resto M, Gerratana B. LaRonde-LeBlanc N, et al. Among authors: gerratana b. Nat Struct Mol Biol. 2009 Apr;16(4):421-9. doi: 10.1038/nsmb.1567. Epub 2009 Mar 8. Nat Struct Mol Biol. 2009. PMID: 19270703
Mutasynthesis of a potent anticancer sibiromycin analogue.
Yonemoto IT, Li W, Khullar A, Reixach N, Gerratana B. Yonemoto IT, et al. Among authors: gerratana b. ACS Chem Biol. 2012 Jun 15;7(6):973-7. doi: 10.1021/cb200544u. Epub 2012 Mar 23. ACS Chem Biol. 2012. PMID: 22390171 Free PMC article.
Crystal structure of carbapenam synthetase (CarA).
Miller MT, Gerratana B, Stapon A, Townsend CA, Rosenzweig AC. Miller MT, et al. J Biol Chem. 2003 Oct 17;278(42):40996-1002. doi: 10.1074/jbc.M307901200. Epub 2003 Jul 30. J Biol Chem. 2003. PMID: 12890666
Another member of this family of ATP/Mg2+-dependent enzymes, asparagine synthetase (AS-B), catalyzes intermolecular, rather than intramolecular, amide bond formation in asparagine biosynthesis. ...Each monomer resembles beta-LS and AS-B in overall fold, but key diff …
Another member of this family of ATP/Mg2+-dependent enzymes, asparagine synthetase (AS-B), catalyzes intermolecular, rather than intr …
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