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Regulation of lipid and lipoprotein metabolism by PPAR activators.
Gervois P, Torra IP, Fruchart JC, Staels B. Gervois P, et al. Clin Chem Lab Med. 2000 Jan;38(1):3-11. doi: 10.1515/CCLM.2000.002. Clin Chem Lab Med. 2000. PMID: 10774955 Review.
Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-alpha.
Kockx M, Gervois PP, Poulain P, Derudas B, Peters JM, Gonzalez FJ, Princen HM, Kooistra T, Staels B. Kockx M, et al. Among authors: gervois pp. Blood. 1999 May 1;93(9):2991-8. Blood. 1999. PMID: 10216095
PPARα as a therapeutic target in inflammation-associated diseases.
Gervois P, Mansouri RM. Gervois P, et al. Expert Opin Ther Targets. 2012 Nov;16(11):1113-25. doi: 10.1517/14728222.2012.715633. Epub 2012 Aug 27. Expert Opin Ther Targets. 2012. PMID: 22925108 Review.
Liver X receptor activation potentiates the lipopolysaccharide response in human macrophages.
Fontaine C, Rigamonti E, Nohara A, Gervois P, Teissier E, Fruchart JC, Staels B, Chinetti-Gbaguidi G. Fontaine C, et al. Among authors: gervois p. Circ Res. 2007 Jul 6;101(1):40-9. doi: 10.1161/CIRCRESAHA.106.135814. Epub 2007 May 31. Circ Res. 2007. PMID: 17540978
Systemic and distal repercussions of liver-specific peroxisome proliferator-activated receptor-alpha control of the acute-phase response.
Mansouri RM, Baugé E, Staels B, Gervois P. Mansouri RM, et al. Among authors: gervois p. Endocrinology. 2008 Jun;149(6):3215-23. doi: 10.1210/en.2007-1339. Epub 2008 Mar 6. Endocrinology. 2008. PMID: 18325987
Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators.
Vu-Dac N, Gervois P, Jakel H, Nowak M, Bauge E, Dehondt H, Staels B, Pennacchio LA, Rubin EM, Fruchart-Najib J, Fruchart JC. Vu-Dac N, et al. Among authors: gervois p. J Biol Chem. 2003 May 16;278(20):17982-5. doi: 10.1074/jbc.M212191200. Epub 2003 Mar 12. J Biol Chem. 2003. PMID: 12637506
The orphan nuclear receptor Rev-Erbalpha is a peroxisome proliferator-activated receptor (PPAR) gamma target gene and promotes PPARgamma-induced adipocyte differentiation.
Fontaine C, Dubois G, Duguay Y, Helledie T, Vu-Dac N, Gervois P, Soncin F, Mandrup S, Fruchart JC, Fruchart-Najib J, Staels B. Fontaine C, et al. Among authors: gervois p. J Biol Chem. 2003 Sep 26;278(39):37672-80. doi: 10.1074/jbc.M304664200. Epub 2003 Jun 23. J Biol Chem. 2003. PMID: 12821652
Atheroprotective effect of human apolipoprotein A5 in a mouse model of mixed dyslipidemia.
Mansouri RM, Baugé E, Gervois P, Fruchart-Najib J, Fiévet C, Staels B, Fruchart JC. Mansouri RM, et al. Among authors: gervois p. Circ Res. 2008 Aug 29;103(5):450-3. doi: 10.1161/CIRCRESAHA.108.179861. Epub 2008 Jul 24. Circ Res. 2008. PMID: 18658049
Modulation of hepatic inflammatory risk markers of cardiovascular diseases by PPAR-alpha activators: clinical and experimental evidence.
Zambon A, Gervois P, Pauletto P, Fruchart JC, Staels B. Zambon A, et al. Among authors: gervois p. Arterioscler Thromb Vasc Biol. 2006 May;26(5):977-86. doi: 10.1161/01.ATV.0000204327.96431.9a. Epub 2006 Jan 19. Arterioscler Thromb Vasc Biol. 2006. PMID: 16424352 Review.
Drug Insight: mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors.
Gervois P, Fruchart JC, Staels B. Gervois P, et al. Nat Clin Pract Endocrinol Metab. 2007 Feb;3(2):145-56. doi: 10.1038/ncpendmet0397. Nat Clin Pract Endocrinol Metab. 2007. PMID: 17237841 Review.
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