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Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease.
Nlandu-Khodo S, Osaki Y, Scarfe L, Yang H, Phillips-Mignemi M, Tonello J, Saito-Diaz K, Neelisetty S, Ivanova A, Huffstater T, McMahon R, Taketo MM, deCaestecker M, Kasinath B, Harris RC, Lee E, Gewin LS. Nlandu-Khodo S, et al. Among authors: gewin ls. JCI Insight. 2020 May 21;5(10):e135454. doi: 10.1172/jci.insight.135454. JCI Insight. 2020. PMID: 32369448 Free PMC article.
Blocking TGF-β and β-Catenin Epithelial Crosstalk Exacerbates CKD.
Nlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LS. Nlandu-Khodo S, et al. Among authors: gewin ls. J Am Soc Nephrol. 2017 Dec;28(12):3490-3503. doi: 10.1681/ASN.2016121351. Epub 2017 Jul 12. J Am Soc Nephrol. 2017. PMID: 28701516 Free PMC article.
Renal fibrosis: Primacy of the proximal tubule.
Gewin LS. Gewin LS. Matrix Biol. 2018 Aug;68-69:248-262. doi: 10.1016/j.matbio.2018.02.006. Epub 2018 Feb 6. Matrix Biol. 2018. PMID: 29425694 Free PMC article. Review.
Novel kidney dissociation protocol and image-based flow cytometry facilitate improved analysis of injured proximal tubules.
Manolopoulou M, Matlock BK, Nlandu-Khodo S, Simmons AJ, Lau KS, Phillips-Mignemi M, Ivanova A, Alford CE, Flaherty DK, Gewin LS. Manolopoulou M, et al. Among authors: gewin ls. Am J Physiol Renal Physiol. 2019 May 1;316(5):F847-F855. doi: 10.1152/ajprenal.00354.2018. Epub 2019 Feb 13. Am J Physiol Renal Physiol. 2019. PMID: 30759021 Free PMC article.
Inactivation of Tsc2 in Abcg2 lineage-derived cells drives the appearance of polycystic lesions and fibrosis in the adult kidney.
Gewin LS, Summers ME, Harral JW, Gaskill CF, Khodo SN, Neelisetty S, Sullivan TM, Hopp K, Reese JJ, Klemm DJ, Kon V, Ess KC, Shi W, Majka SM. Gewin LS, et al. Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1201-F1210. doi: 10.1152/ajprenal.00629.2018. Epub 2019 Aug 28. Am J Physiol Renal Physiol. 2019. PMID: 31461347 Free PMC article.
27 results