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The sema domain.
Gherardi E, Love CA, Esnouf RM, Jones EY. Gherardi E, et al. Curr Opin Struct Biol. 2004 Dec;14(6):669-78. doi: 10.1016/ Curr Opin Struct Biol. 2004. PMID: 15582390 Review.
Engineering the NK1 fragment of hepatocyte growth factor/scatter factor as a MET receptor antagonist.
Youles M, Holmes O, Petoukhov MV, Nessen MA, Stivala S, Svergun DI, Gherardi E. Youles M, et al. Among authors: gherardi e. J Mol Biol. 2008 Mar 28;377(3):616-22. doi: 10.1016/j.jmb.2008.01.034. Epub 2008 Jan 18. J Mol Biol. 2008. PMID: 18291418
A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping.
Watanabe K, Chirgadze DY, Lietha D, de Jonge H, Blundell TL, Gherardi E. Watanabe K, et al. Among authors: gherardi e. J Mol Biol. 2002 May 31;319(2):283-8. doi: 10.1016/S0022-2836(02)00199-7. J Mol Biol. 2002. PMID: 12051906
Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains.
Holmes O, Pillozzi S, Deakin JA, Carafoli F, Kemp L, Butler PJ, Lyon M, Gherardi E. Holmes O, et al. Among authors: gherardi e. J Mol Biol. 2007 Mar 23;367(2):395-408. doi: 10.1016/j.jmb.2006.12.061. Epub 2007 Jan 26. J Mol Biol. 2007. PMID: 17258232
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.
Chirgadze DY, Hepple JP, Zhou H, Byrd RA, Blundell TL, Gherardi E. Chirgadze DY, et al. Among authors: gherardi e. Nat Struct Biol. 1999 Jan;6(1):72-9. doi: 10.1038/4947. Nat Struct Biol. 1999. PMID: 9886295
Structural repertoire of the human VH segments.
Chothia C, Lesk AM, Gherardi E, Tomlinson IM, Walter G, Marks JD, Llewelyn MB, Winter G. Chothia C, et al. Among authors: gherardi e. J Mol Biol. 1992 Oct 5;227(3):799-817. doi: 10.1016/0022-2836(92)90224-8. J Mol Biol. 1992. PMID: 1404389
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