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Naphthalene-fused (α-alkoxycarbonyl)methylene-γ-butyrolactones: antiproliferative activity and binding to bovine serum albumin and DNA.
Rajabi M, Khalilzadeh MA, Tavakolinia F, Signorelli P, Ghidoni R, Santaniello E. Rajabi M, et al. DNA Cell Biol. 2012 May;31(5):783-9. doi: 10.1089/dna.2011.1433. Epub 2011 Nov 10. DNA Cell Biol. 2012. PMID: 22074127
Antiproliferative activity and cell cycle analysis of 2-(3,5-dihydroxyphenyl)-6-hydroxybenzothiazole on MCF-7 breast and HCT-15 colon cancer cell lines.
Rajabi M, Minutolo F, Bertini S, Macchia M, Ghidoni R. Rajabi M, et al. DNA Cell Biol. 2011 Aug;30(8):617-21. doi: 10.1089/dna.2011.1220. Epub 2011 Mar 25. DNA Cell Biol. 2011. PMID: 21438664
Synthesis of a resveratrol analogue with high ceramide-mediated proapoptotic activity on human breast cancer cells.
Minutolo F, Sala G, Bagnacani A, Bertini S, Carboni I, Placanica G, Prota G, Rapposelli S, Sacchi N, Macchia M, Ghidoni R. Minutolo F, et al. J Med Chem. 2005 Nov 3;48(22):6783-6. doi: 10.1021/jm050528k. J Med Chem. 2005. PMID: 16250636
Breast cancer and sphingolipid signalling.
Signorelli P, Ghidoni R. Signorelli P, et al. J Dairy Res. 2005;72 Spec No:5-13. doi: 10.1017/s0022029905001238. J Dairy Res. 2005. PMID: 16180715 Review. No abstract available.
Resveratrol impairs the formation of MDA-MB-231 multicellular tumor spheroids concomitant with ceramide accumulation.
Dolfini E, Roncoroni L, Dogliotti E, Sala G, Erba E, Sacchi N, Ghidoni R. Dolfini E, et al. Cancer Lett. 2007 May 8;249(2):143-7. doi: 10.1016/j.canlet.2006.08.013. Epub 2006 Sep 22. Cancer Lett. 2007. PMID: 16996206
Natural grape extracts regulate colon cancer cells malignancy.
Signorelli P, Fabiani C, Brizzolari A, Paroni R, Casas J, Fabriàs G, Rossi D, Ghidoni R, Caretti A. Signorelli P, et al. Nutr Cancer. 2015;67(3):494-503. doi: 10.1080/01635581.2015.1004591. Epub 2015 Feb 23. Nutr Cancer. 2015. PMID: 25705818
Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy.
Gagliostro V, Casas J, Caretti A, Abad JL, Tagliavacca L, Ghidoni R, Fabrias G, Signorelli P. Gagliostro V, et al. Int J Biochem Cell Biol. 2012 Dec;44(12):2135-43. doi: 10.1016/j.biocel.2012.08.025. Epub 2012 Sep 7. Int J Biochem Cell Biol. 2012. PMID: 22960157
Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells.
Signorelli P, Munoz-Olaya JM, Gagliostro V, Casas J, Ghidoni R, Fabriàs G. Signorelli P, et al. Cancer Lett. 2009 Sep 18;282(2):238-43. doi: 10.1016/j.canlet.2009.03.020. Epub 2009 Apr 25. Cancer Lett. 2009. PMID: 19394759
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