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340 results
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Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER).
Porter JR, Lockwood SH, Segal DJ, Ghosh I. Porter JR, et al. Among authors: ghosh i. Methods Mol Biol. 2010;649:365-82. doi: 10.1007/978-1-60761-753-2_23. Methods Mol Biol. 2010. PMID: 20680847
Small molecule gated split-tyrosine phosphatases and orthogonal split-tyrosine kinases.
Camacho-Soto K, Castillo-Montoya J, Tye B, Ogunleye LO, Ghosh I. Camacho-Soto K, et al. Among authors: ghosh i. J Am Chem Soc. 2014 Dec 10;136(49):17078-86. doi: 10.1021/ja5080745. Epub 2014 Nov 26. J Am Chem Soc. 2014. PMID: 25409264
Split-protein systems: beyond binary protein-protein interactions.
Shekhawat SS, Ghosh I. Shekhawat SS, et al. Among authors: ghosh i. Curr Opin Chem Biol. 2011 Dec;15(6):789-97. doi: 10.1016/j.cbpa.2011.10.014. Epub 2011 Nov 7. Curr Opin Chem Biol. 2011. PMID: 22070901 Free PMC article. Review.
Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.
Furman JL, Mok PW, Badran AH, Ghosh I. Furman JL, et al. Among authors: ghosh i. J Am Chem Soc. 2011 Aug 17;133(32):12518-27. doi: 10.1021/ja1116606. Epub 2011 May 17. J Am Chem Soc. 2011. PMID: 21520929 Free PMC article.
Toward a general approach for RNA-templated hierarchical assembly of split-proteins.
Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Furman JL, et al. Among authors: ghosh i. J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b. J Am Chem Soc. 2010. PMID: 20681585 Free PMC article.
DNA sequence-enabled reassembly of the green fluorescent protein.
Stains CI, Porter JR, Ooi AT, Segal DJ, Ghosh I. Stains CI, et al. Among authors: ghosh i. J Am Chem Soc. 2005 Aug 10;127(31):10782-3. doi: 10.1021/ja051969w. J Am Chem Soc. 2005. PMID: 16076155
Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.
Badran AH, Furman JL, Ma AS, Comi TJ, Porter JR, Ghosh I. Badran AH, et al. Among authors: ghosh i. Anal Chem. 2011 Sep 15;83(18):7151-7. doi: 10.1021/ac2015239. Epub 2011 Aug 23. Anal Chem. 2011. PMID: 21797230 Free PMC article.
A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases.
Jester BW, Cox KJ, Gaj A, Shomin CD, Porter JR, Ghosh I. Jester BW, et al. Among authors: ghosh i. J Am Chem Soc. 2010 Aug 25;132(33):11727-35. doi: 10.1021/ja104491h. J Am Chem Soc. 2010. PMID: 20669947 Free PMC article.
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Furman JL, et al. Among authors: ghosh i. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3748-51. doi: 10.1016/j.bmcl.2009.04.141. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19457665 Free PMC article.
A general and rapid cell-free approach for the interrogation of protein-protein, protein-DNA, and protein-RNA interactions and their antagonists utilizing split-protein reporters.
Porter JR, Stains CI, Jester BW, Ghosh I. Porter JR, et al. Among authors: ghosh i. J Am Chem Soc. 2008 May 21;130(20):6488-97. doi: 10.1021/ja7114579. Epub 2008 Apr 29. J Am Chem Soc. 2008. PMID: 18444624
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