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1996 3
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13,847 results

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Page 1
Ghrelin's Relationship to Blood Glucose.
Mani BK, Shankar K, Zigman JM. Mani BK, et al. Endocrinology. 2019 May 1;160(5):1247-1261. doi: 10.1210/en.2019-00074. Endocrinology. 2019. PMID: 30874792 Free PMC article. Review.
Much effort has been directed at studying the orexigenic actions of administered ghrelin and the potential effects of the endogenous ghrelin system on food intake, food reward, body weight, adiposity, and energy expenditure. Although endogenous ghrelin's …
Much effort has been directed at studying the orexigenic actions of administered ghrelin and the potential effects of the endogenous …
Ghrelin mediated hippocampal neurogenesis.
Davies JS. Davies JS. Vitam Horm. 2022;118:337-367. doi: 10.1016/bs.vh.2021.12.003. Epub 2022 Jan 27. Vitam Horm. 2022. PMID: 35180932 Review.
The stomach hormone, ghrelin, which is released during food restriction, provides a link between circulating energy state and adaptive brain function. ...Here, we review current developments in our understanding of ghrelin's role in regulating neurogenesis an …
The stomach hormone, ghrelin, which is released during food restriction, provides a link between circulating energy state and adaptiv …
Ghrelin regulation of glucose metabolism.
Gray SM, Page LC, Tong J. Gray SM, et al. J Neuroendocrinol. 2019 Jul;31(7):e12705. doi: 10.1111/jne.12705. Epub 2019 Apr 3. J Neuroendocrinol. 2019. PMID: 30849212 Free PMC article. Review.
Although many studies have explored the role of ghrelin in glucose tolerance and insulin secretion, a complete mechanistic understanding remains to be clarified. ...Additionally, we discuss the effect of ghrelin on in vivo glucose metabolism in rodents and humans, a …
Although many studies have explored the role of ghrelin in glucose tolerance and insulin secretion, a complete mechanistic understand …
Ghrelin as a prominent endocrine factor in stress-induced obesity.
van Loenen MR, Geenen B, Arnoldussen IAC, Kiliaan AJ. van Loenen MR, et al. Nutr Neurosci. 2022 Jul;25(7):1413-1424. doi: 10.1080/1028415X.2020.1863740. Epub 2020 Dec 29. Nutr Neurosci. 2022. PMID: 33373270 Free article. Review.
Recent studies have indicated that ghrelin's function as an orexigenic agent does not entirely reflect the full functional properties of the peptide. Specifically, ghrelin regulates stress-hormone synthesis and secretion therewith affecting the stress-axis. . …
Recent studies have indicated that ghrelin's function as an orexigenic agent does not entirely reflect the full functional pro …
Ghrelin-LEAP2 interactions along the stomach-liver axis.
Sakai K, Nakazato Y, Shiimura Y, Zhang W, Nakazato M. Sakai K, et al. Endocr J. 2025 Apr 1;72(4):341-353. doi: 10.1507/endocrj.EJ24-0543. Epub 2024 Dec 27. Endocr J. 2025. PMID: 39756956 Free PMC article. Review.
Anamorelin, a low-molecular-weight ghrelin agonist, has been launched in Japan for the treatment of cancer cachexia, and its therapeutic potential has attracted attention due to the various biological activities of ghrelin. ...LEAP2 binds to the GHSR and antagonizes …
Anamorelin, a low-molecular-weight ghrelin agonist, has been launched in Japan for the treatment of cancer cachexia, and its therapeu …
Ghrelin and cancer progression.
Lin TC, Hsiao M. Lin TC, et al. Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):51-57. doi: 10.1016/j.bbcan.2017.02.002. Epub 2017 Feb 24. Biochim Biophys Acta Rev Cancer. 2017. PMID: 28238732 Free article. Review.
Emerging evidences have revealed ghrelin's function in regulating several processes related to cancer progression, especially in metastasis and proliferation. We further show the relative GHRL and GHSR expression in pan-cancers from The Cancer Genome Atlas (TCGA), s …
Emerging evidences have revealed ghrelin's function in regulating several processes related to cancer progression, especially …
Ghrelin: An Emerging Therapy for Heart Failure.
Theodorakis N, Feretzakis G, Kreouzi M, Anagnostou D, Hitas C, Verykios VS, Nikolaou M. Theodorakis N, et al. Clin Endocrinol (Oxf). 2025 Apr;102(4):403-412. doi: 10.1111/cen.15196. Epub 2025 Jan 5. Clin Endocrinol (Oxf). 2025. PMID: 39757711 Free PMC article. Review.
OBJECTIVE: Ghrelin is emerging as a promising therapeutic option for heart failure (HF) due to its potent inotropic, anabolic, and cardioprotective properties. ...RESULTS: Clinical trials investigating ghrelin's acute effects in HF patients have demonstrated …
OBJECTIVE: Ghrelin is emerging as a promising therapeutic option for heart failure (HF) due to its potent inotropic, anabolic, and ca …
Ghrelin-Mediated Hippocampal Neurogenesis: Implications for Health and Disease.
Buntwal L, Sassi M, Morgan AH, Andrews ZB, Davies JS. Buntwal L, et al. Trends Endocrinol Metab. 2019 Nov;30(11):844-859. doi: 10.1016/j.tem.2019.07.001. Epub 2019 Aug 21. Trends Endocrinol Metab. 2019. PMID: 31445747 Review.
There is a close relationship between cognition and nutritional status, however, the mechanisms underlying this relationship require elucidation. The stomach hormone, ghrelin, which is released during food restriction, provides a link between circulating energy state and a …
There is a close relationship between cognition and nutritional status, however, the mechanisms underlying this relationship require elucida …
Ghrelin Acylation-A Post-Translational Tuning Mechanism Regulating Adult Hippocampal Neurogenesis.
Sassi M, Morgan AH, Davies JS. Sassi M, et al. Cells. 2022 Feb 22;11(5):765. doi: 10.3390/cells11050765. Cells. 2022. PMID: 35269387 Free PMC article. Review.
We recently showed that the acylated version of the gut hormone ghrelin (acyl-ghrelin) stimulates adult hippocampal neurogenesis while the unacylated form of ghrelin inhibits it, thus demonstrating a previously unknown function of unacyl-ghrelin in mod …
We recently showed that the acylated version of the gut hormone ghrelin (acyl-ghrelin) stimulates adult hippocampal neurogenes …
Ghrelin in Depression: A Promising Therapeutic Target.
Kore MS, Mamsa R, Patil D, Bhatt LK. Kore MS, et al. Mol Neurobiol. 2025 Apr;62(4):4237-4249. doi: 10.1007/s12035-024-04554-1. Epub 2024 Oct 18. Mol Neurobiol. 2025. PMID: 39424690 Review.
Ghrelin release is also affected by the gut microbes, which has also been discussed in the review. This review elaborates on Ghrelin's role in depression and its effect on various aspects like neurogenesis, HPA axis, and neuroinflammation. ...
Ghrelin release is also affected by the gut microbes, which has also been discussed in the review. This review elaborates on Ghrel …
13,847 results
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