Giacomini KM - Search Results

1

Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.

Schlessinger A, Geier E, Fan H, Irwin JJ, Shoichet BK, Giacomini KM, Sali A. Schlessinger A, et al. Among authors: giacomini km. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15810-5. doi: 10.1073/pnas.1106030108. Epub 2011 Sep 1. Proc Natl Acad Sci U S A. 2011. PMID: 21885739 Free PMC article.

2

Natural variation in human membrane transporter genes reveals evolutionary and functional constraints.

Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, Giacomini KM; Pharmacogenetics Of Membrane Transporters Investigators. Leabman MK, et al. Among authors: giacomini km. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5896-901. doi: 10.1073/pnas.0730857100. Epub 2003 Apr 28. Proc Natl Acad Sci U S A. 2003. PMID: 12719533 Free PMC article.

3

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1.

Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM; Pharmacogenetics Of Membrane Transporters Investigators. Shu Y, et al. Among authors: giacomini km. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5902-7. doi: 10.1073/pnas.0730858100. Epub 2003 Apr 28. Proc Natl Acad Sci U S A. 2003. PMID: 12719534 Free PMC article.

4

PharmGKB submission update: IV. PMT submissions of genetic variations in ATP-Binding cassette transporters to the PharmGKB network.

Nguyen TD, Gow JM, Chinn LW, Kelly L, Jeong H, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson E, Taylor T, Ferrin TE, Sali A, Giacomini KM, Kroetz DL. Nguyen TD, et al. Among authors: giacomini km. Pharmacol Rev. 2006 Mar;58(1):1-2. doi: 10.1124/pr.58.1.1. Pharmacol Rev. 2006. PMID: 16507877 No abstract available.

5

Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations.

Huang N, Agrawal V, Giacomini KM, Miller WL. Huang N, et al. Among authors: giacomini km. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1733-8. doi: 10.1073/pnas.0711621105. Epub 2008 Jan 29. Proc Natl Acad Sci U S A. 2008. PMID: 18230729 Free PMC article.

6

Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening.

Li M, Hays FA, Roe-Zurz Z, Vuong L, Kelly L, Ho CM, Robbins RM, Pieper U, O'Connell JD 3rd, Miercke LJ, Giacomini KM, Sali A, Stroud RM. Li M, et al. Among authors: giacomini km. J Mol Biol. 2009 Jan 23;385(3):820-30. doi: 10.1016/j.jmb.2008.11.021. Epub 2008 Nov 24. J Mol Biol. 2009. PMID: 19061901 Free PMC article.

7

A survey of integral alpha-helical membrane proteins.

Kelly L, Pieper U, Eswar N, Hays FA, Li M, Roe-Zurz Z, Kroetz DL, Giacomini KM, Stroud RM, Sali A. Kelly L, et al. Among authors: giacomini km. J Struct Funct Genomics. 2009 Dec;10(4):269-80. doi: 10.1007/s10969-009-9069-8. Epub 2009 Sep 17. J Struct Funct Genomics. 2009. PMID: 19760129 Free PMC article.

8

Institutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy.

Kroetz DL, Ahituv N, Burchard EG, Guo S, Sali A, Giacomini KM. Kroetz DL, et al. Among authors: giacomini km. Pharmacogenomics. 2009 Oct;10(10):1569-76. doi: 10.2217/pgs.09.119. Pharmacogenomics. 2009. PMID: 19842929 Free PMC article.

9

Comparison of human solute carriers.

Schlessinger A, Matsson P, Shima JE, Pieper U, Yee SW, Kelly L, Apeltsin L, Stroud RM, Ferrin TE, Giacomini KM, Sali A. Schlessinger A, et al. Among authors: giacomini km. Protein Sci. 2010 Mar;19(3):412-28. doi: 10.1002/pro.320. Protein Sci. 2010. PMID: 20052679 Free PMC article.

10

Role of the copper transporter, CTR1, in platinum-induced ototoxicity.

More SS, Akil O, Ianculescu AG, Geier EG, Lustig LR, Giacomini KM. More SS, et al. Among authors: giacomini km. J Neurosci. 2010 Jul 14;30(28):9500-9. doi: 10.1523/JNEUROSCI.1544-10.2010. J Neurosci. 2010. PMID: 20631178 Free PMC article.

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