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Functional genetic diversity in the high-affinity carnitine transporter OCTN2 (SLC22A5).
Urban TJ, Gallagher RC, Brown C, Castro RA, Lagpacan LL, Brett CM, Taylor TR, Carlson EJ, Ferrin TE, Burchard EG, Packman S, Giacomini KM. Urban TJ, et al. Mol Pharmacol. 2006 Nov;70(5):1602-11. doi: 10.1124/mol.106.028126. Epub 2006 Aug 24. Mol Pharmacol. 2006. PMID: 16931768
Pharmacogenomics: challenges and opportunities.
Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, Johnson JA, Krauss RM, McLeod HL, Ratain MJ, Relling MV, Ring HZ, Shuldiner AR, Weinshilboum RM, Weiss ST; Pharmacogenetics Research Network. Roden DM, et al. Ann Intern Med. 2006 Nov 21;145(10):749-57. doi: 10.7326/0003-4819-145-10-200611210-00007. Ann Intern Med. 2006. PMID: 17116919 Free PMC article. Review.
Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP.
Cropp CD, Komori T, Shima JE, Urban TJ, Yee SW, More SS, Giacomini KM. Cropp CD, et al. Mol Pharmacol. 2008 Apr;73(4):1151-8. doi: 10.1124/mol.107.043117. Epub 2008 Jan 23. Mol Pharmacol. 2008. PMID: 18216183 Free PMC article.
Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).
Yee SW, Shima JE, Hesselson S, Nguyen L, De Val S, Lafond RJ, Kawamoto M, Johns SJ, Stryke D, Kwok PY, Ferrin TE, Black BL, Gurwitz D, Ahituv N, Giacomini KM. Yee SW, et al. J Pharmacol Exp Ther. 2009 Mar;328(3):699-707. doi: 10.1124/jpet.108.147207. Epub 2008 Dec 19. J Pharmacol Exp Ther. 2009. PMID: 19098160 Free PMC article.
Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5).
Tahara H, Yee SW, Urban TJ, Hesselson S, Castro RA, Kawamoto M, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Giacomini KM. Tahara H, et al. J Pharmacol Exp Ther. 2009 Apr;329(1):262-71. doi: 10.1124/jpet.108.146449. Epub 2009 Jan 13. J Pharmacol Exp Ther. 2009. PMID: 19141711 Free PMC article.
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