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Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling.
Sci Adv. 2025 May 9;11(19):eadn2528. doi: 10.1126/sciadv.adn2528. Epub 2025 May 9.
Sci Adv. 2025.
PMID: 40344059
Free PMC article.
Disruption of mitochondrial homeostasis and permeability transition pore opening in OPA1 iPSC-derived retinal ganglion cells.
Whitehead M, Harvey JP, Sladen PE, Becchi G, Singh K, Sun YJ, Burgoyne T, Duchen MR, Yu-Wai-Man P, Cheetham ME.
Whitehead M, et al. Among authors: becchi g.
Acta Neuropathol Commun. 2025 Feb 13;13(1):28. doi: 10.1186/s40478-025-01942-z.
Acta Neuropathol Commun. 2025.
PMID: 39948685
Free PMC article.
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CRISPRa-Mediated Increase of OPA1 Expression in Dominant Optic Atrophy.
Becchi G, Whitehead M, Harvey JP, Sladen PE, Dushti M, Chapple JP, Yu-Wai-Man P, Cheetham ME.
Becchi G, et al.
Int J Mol Sci. 2025 Jul 2;26(13):6364. doi: 10.3390/ijms26136364.
Int J Mol Sci. 2025.
PMID: 40650142
Free PMC article.
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