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NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species.
Giardina C, Boulares H, Inan MS. Giardina C, et al. Biochim Biophys Acta. 1999 Jan 11;1448(3):425-38. doi: 10.1016/s0167-4889(98)00156-6. Biochim Biophys Acta. 1999. PMID: 9990295
The dual chemopreventive agent/death ligand treatments do not increase Fas, TNF receptor 1, Bak or c-myc expression (although salicylic acid moderately induces of Fas expression). ...The effects of NAC on TNF-alpha-induced cell death are more complex, with NAC being margin …
The dual chemopreventive agent/death ligand treatments do not increase Fas, TNF receptor 1, Bak or c-myc expression (although salicyl …
HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling.
Godman CA, Joshi R, Tierney BR, Greenspan E, Rasmussen TP, Wang HW, Shin DG, Rosenberg DW, Giardina C. Godman CA, et al. Among authors: giardina c. Cancer Biol Ther. 2008 Oct;7(10):1570-80. doi: 10.4161/cbt.7.10.6561. Epub 2008 Oct 7. Cancer Biol Ther. 2008. PMID: 18769117 Free PMC article.
Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands.
Chopra AS, Kuratnik A, Scocchera EW, Wright DL, Giardina C. Chopra AS, et al. Among authors: giardina c. Cancer Biol Ther. 2013 May;14(5):436-49. doi: 10.4161/cbt.23787. Epub 2013 Feb 1. Cancer Biol Ther. 2013. PMID: 23377828 Free PMC article.
Hyperbaric oxygen treatment induces antioxidant gene expression.
Godman CA, Joshi R, Giardina C, Perdrizet G, Hightower LE. Godman CA, et al. Among authors: giardina c. Ann N Y Acad Sci. 2010 Jun;1197:178-83. doi: 10.1111/j.1749-6632.2009.05393.x. Ann N Y Acad Sci. 2010. PMID: 20536847 Review.
Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells.
Godman CA, Chheda KP, Hightower LE, Perdrizet G, Shin DG, Giardina C. Godman CA, et al. Among authors: giardina c. Cell Stress Chaperones. 2010 Jul;15(4):431-42. doi: 10.1007/s12192-009-0159-0. Epub 2009 Dec 1. Cell Stress Chaperones. 2010. PMID: 19949909 Free PMC article.
Hsp70B' regulation and function.
Noonan EJ, Place RF, Giardina C, Hightower LE. Noonan EJ, et al. Among authors: giardina c. Cell Stress Chaperones. 2007 Autumn;12(3):219-29. doi: 10.1379/csc-278.1. Cell Stress Chaperones. 2007. PMID: 17915554 Free PMC article. Corrected and republished.
Cyclooxygenase-2 regulation in colon cancer cells: modulation of RNA polymerase II elongation by histone deacetylase inhibitors.
Tong X, Yin L, Joshi S, Rosenberg DW, Giardina C. Tong X, et al. Among authors: giardina c. J Biol Chem. 2005 Apr 22;280(16):15503-9. doi: 10.1074/jbc.M411978200. Epub 2005 Feb 15. J Biol Chem. 2005. PMID: 15713675
Because butyrate has been reported to suppress polymerase elongation on the c-myc gene, we employed the chromatin immunoprecipitation assay to determine the influence of butyrate and trichostatin A on polymerase distribution on the Cox-2 gene. These data indicated that but …
Because butyrate has been reported to suppress polymerase elongation on the c-myc gene, we employed the chromatin immunoprecipitation …
Growing old with nuclear factor-kappaB.
Giardina C, Hubbard AK. Giardina C, et al. Cell Stress Chaperones. 2002 Apr;7(2):207-12. doi: 10.1379/1466-1268(2002)007<0207:gownfb>2.0.co;2. Cell Stress Chaperones. 2002. PMID: 12380689 Free PMC article. Review.
Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation.
Place RF, Haspeslagh D, Giardina C. Place RF, et al. Among authors: giardina c. J Cell Physiol. 2003 Jun;195(3):470-8. doi: 10.1002/jcp.10262. J Cell Physiol. 2003. PMID: 12704657
The TNF-alpha-induced stabilization of newly synthesized IkappaBalpha involves the C-terminal PEST region of the protein: N-terminal deletion mutants (lacking the IkappaB kinase phosphorylation sites) were readily stabilized by TNF-alpha, whereas deletion of the C-t …
The TNF-alpha-induced stabilization of newly synthesized IkappaBalpha involves the C-terminal PEST region of the protein: N-terminal …
Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301.
Chopra A, Bond MJ, Bleiler M, Yeagley M, Wright D, Giardina C. Chopra A, et al. Among authors: giardina c. PLoS One. 2016 Apr 20;11(4):e0153818. doi: 10.1371/journal.pone.0153818. eCollection 2016. PLoS One. 2016. PMID: 27097159 Free PMC article.
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