Gibbs R - Search Results

1

Inhibition of glucose- and calcium-induced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation.

Amin R, Chen HQ, Tannous M, Gibbs R, Kowluru A. Amin R, et al. Among authors: gibbs r. J Pharmacol Exp Ther. 2002 Oct;303(1):82-8. doi: 10.1124/jpet.102.036160. J Pharmacol Exp Ther. 2002. PMID: 12235236

2

Working together: Farnesyl transferase inhibitors and statins block protein prenylation.

Wojtkowiak JW, Gibbs RA, Mattingly RR. Wojtkowiak JW, et al. Among authors: gibbs ra. Mol Cell Pharmacol. 2009 Jan 1;1(1):1-6. doi: 10.4255/mcpharmacol.09.01. Mol Cell Pharmacol. 2009. PMID: 20419048 Free PMC article.

3

A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells.

Sane KM, Mynderse M, Lalonde DT, Dean IS, Wojtkowiak JW, Fouad F, Borch RF, Reiners JJ Jr, Gibbs RA, Mattingly RR. Sane KM, et al. Among authors: gibbs ra. J Pharmacol Exp Ther. 2010 Apr;333(1):23-33. doi: 10.1124/jpet.109.160192. Epub 2010 Jan 19. J Pharmacol Exp Ther. 2010. PMID: 20086055 Free PMC article.

4

Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1.

Dilworth JT, Kraniak JM, Wojtkowiak JW, Gibbs RA, Borch RF, Tainsky MA, Reiners JJ Jr, Mattingly RR. Dilworth JT, et al. Among authors: gibbs ra. Biochem Pharmacol. 2006 Nov 30;72(11):1485-92. doi: 10.1016/j.bcp.2006.04.010. Epub 2006 Apr 28. Biochem Pharmacol. 2006. PMID: 16797490 Review.

5

Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin.

Wojtkowiak JW, Fouad F, LaLonde DT, Kleinman MD, Gibbs RA, Reiners JJ Jr, Borch RF, Mattingly RR. Wojtkowiak JW, et al. Among authors: gibbs ra. J Pharmacol Exp Ther. 2008 Jul;326(1):1-11. doi: 10.1124/jpet.107.135830. Epub 2008 Mar 26. J Pharmacol Exp Ther. 2008. PMID: 18367665 Free PMC article.

6

Potent suppression of proliferation of a10 vascular smooth muscle cells by combined treatment with lovastatin and 3-allylfarnesol, an inhibitor of protein farnesyltransferase.

Mattingly RR, Gibbs RA, Menard RE, Reiners JJ Jr. Mattingly RR, et al. Among authors: gibbs ra. J Pharmacol Exp Ther. 2002 Oct;303(1):74-81. doi: 10.1124/jpet.102.036061. J Pharmacol Exp Ther. 2002. PMID: 12235235

7

Interplay of isoprenoid and peptide substrate specificity in protein farnesyltransferase.

Reigard SA, Zahn TJ, Haworth KB, Hicks KA, Fierke CA, Gibbs RA. Reigard SA, et al. Biochemistry. 2005 Aug 23;44(33):11214-23. doi: 10.1021/bi050725l. Biochemistry. 2005. PMID: 16101305

8

Synthesis of 7-substituted farnesyl diphosphate analogues.

Rawat DS, Gibbs RA. Rawat DS, et al. Org Lett. 2002 Sep 5;4(18):3027-30. doi: 10.1021/ol026176i. Org Lett. 2002. PMID: 12201708

9

Aromatic farnesyl diphosphate analogues: vinyl triflate-mediated synthesis and preliminary enzymatic evaluation.

Zhou C, Shao Y, Gibbs RA. Zhou C, et al. Bioorg Med Chem Lett. 2002 May 20;12(10):1417-20. doi: 10.1016/s0960-894x(02)00187-7. Bioorg Med Chem Lett. 2002. PMID: 11992789

10

Coupling of isoprenoid triflates with organoboron nucleophiles: synthesis and biological evaluation of geranylgeranyl diphosphate analogues.

Mu Y, Eubanks LM, Poulter CD, Gibbs RA. Mu Y, et al. Bioorg Med Chem. 2002 May;10(5):1207-19. doi: 10.1016/s0968-0896(01)00390-x. Bioorg Med Chem. 2002. PMID: 11886785

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