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Page 1
Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.
Headland SE, Dengler HS, Xu D, Teng G, Everett C, Ratsimandresy RA, Yan D, Kang J, Ganeshan K, Nazarova EV, Gierke S, Wedeles CJ, Guidi R, DePianto DJ, Morshead KB, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Klementowicz JE, Shi Y, Wang J, Bevers J 3rd, Ramirez-Carrozzi V, Pappu R, Abbas A, Vander Heiden J, Choy DF, Yadav R, Modrusan Z, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Jenkins BJ, Cao Y, Clarke C, Austin C, Lafkas D, Xu M, Wolters PJ, Arron JR, West NR, Wilson MS. Headland SE, et al. Among authors: gierke s. Sci Transl Med. 2022 Jan 12;14(627):eabf8188. doi: 10.1126/scitranslmed.abf8188. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020406
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis.
Xi Y, LaCanna R, Ma HY, N'Diaye EN, Gierke S, Caplazi P, Sagolla M, Huang Z, Lucio L, Arlantico A, Jeet S, Brightbill H, Emson C, Wong A, Morshead KB, DePianto DJ, Roose-Girma M, Yu C, Tam L, Jia G, Ramalingam TR, Marsters S, Ashkenazi A, Kim SH, Kelly R, Wu S, Wolters PJ, Feldstein AE, Vander Heiden JA, Ding N. Xi Y, et al. Among authors: gierke s. Cell Metab. 2022 Sep 6;34(9):1377-1393.e8. doi: 10.1016/j.cmet.2022.07.009. Epub 2022 Aug 19. Cell Metab. 2022. PMID: 35987202 Free article.
Obligate role for Rock1 and Rock2 in adult stem cell viability and function.
Sambandam A, Storm E, Tauc H, Hackney JA, Garfield D, Caplazi P, Liu J, Zhang J, Zhang H, Duggan J, Jeet S, Gierke S, Chang P, Wu X, Newman R, Tam L, Alcantar T, Wang L, Roose-Girma M, Modrusan Z, Lee WP, Jasper H, de Sauvage F, Pappu R. Sambandam A, et al. Among authors: gierke s. Heliyon. 2023 Mar 9;9(3):e14238. doi: 10.1016/j.heliyon.2023.e14238. eCollection 2023 Mar. Heliyon. 2023. PMID: 36950615 Free PMC article.
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.
Dominguez CX, Müller S, Keerthivasan S, Koeppen H, Hung J, Gierke S, Breart B, Foreman O, Bainbridge TW, Castiglioni A, Senbabaoglu Y, Modrusan Z, Liang Y, Junttila MR, Klijn C, Bourgon R, Turley SJ. Dominguez CX, et al. Among authors: gierke s. Cancer Discov. 2020 Feb;10(2):232-253. doi: 10.1158/2159-8290.CD-19-0644. Epub 2019 Nov 7. Cancer Discov. 2020. PMID: 31699795
Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer.
Taraborrelli L, Şenbabaoğlu Y, Wang L, Lim J, Blake K, Kljavin N, Gierke S, Scherl A, Ziai J, McNamara E, Owyong M, Rao S, Calviello AK, Oreper D, Jhunjhunwala S, Argiles G, Bendell J, Kim TW, Ciardiello F, Wongchenko MJ, de Sauvage FJ, de Sousa E Melo F, Yan Y, West NR, Murthy A. Taraborrelli L, et al. Among authors: gierke s. Nat Commun. 2023 Sep 23;14(1):5945. doi: 10.1038/s41467-023-41618-7. Nat Commun. 2023. PMID: 37741832 Free PMC article.
The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.
Abed M, Verschueren E, Budayeva H, Liu P, Kirkpatrick DS, Reja R, Kummerfeld SK, Webster JD, Gierke S, Reichelt M, Anderson KR, Newman RJ, Roose-Girma M, Modrusan Z, Pektas H, Maltepe E, Newton K, Dixit VM. Abed M, et al. Among authors: gierke s. PLoS One. 2019 Apr 5;14(4):e0214110. doi: 10.1371/journal.pone.0214110. eCollection 2019. PLoS One. 2019. PMID: 30951545 Free PMC article.
Toxigenic Clostridium perfringens isolated from at-risk pediatric inflammatory bowel disease patients.
Kuo J, Uzunovic J, Jacobson A, Dourado M, Gierke S, Rajendram M, Keilberg D, Mar J, Stekol E, Curry J, Verstraete S, Lund J, Liang Y, Tamburini FB, Omattage NS, Masureel M, Rutherford ST, Hackos DH, Tan MW, Byrd AL, Keir ME, Skippington E, Storek KM. Kuo J, et al. Among authors: gierke s. J Crohns Colitis. 2024 Jan 24:jjae016. doi: 10.1093/ecco-jcc/jjae016. Online ahead of print. J Crohns Colitis. 2024. PMID: 38267224
The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology.
Astarita JL, Keerthivasan S, Husain B, Şenbabaoğlu Y, Verschueren E, Gierke S, Pham VC, Peterson SM, Chalouni C, Pierce AA, Lill JR, Gonzalez LC, Martinez-Martin N, Turley SJ. Astarita JL, et al. Among authors: gierke s. PLoS One. 2021 Dec 8;16(12):e0260800. doi: 10.1371/journal.pone.0260800. eCollection 2021. PLoS One. 2021. PMID: 34879110 Free PMC article.
21 results