Gilep AA - Search Results

1

Structural insights into aldosterone synthase substrate specificity and targeted inhibition.

Strushkevich N, Gilep AA, Shen L, Arrowsmith CH, Edwards AM, Usanov SA, Park HW. Strushkevich N, et al. Among authors: gilep aa. Mol Endocrinol. 2013 Feb;27(2):315-24. doi: 10.1210/me.2012-1287. Epub 2013 Jan 15. Mol Endocrinol. 2013. PMID: 23322723 Free PMC article.

2

Increasing the Efficiency of Cytochrome P450 3A4 Electrocatalysis Using Electrode Modification with Spatially Ordered Anodic Aluminum Oxide-Based Nanostructures for Investigation of Metabolic Transformations of Drugs.

Shumyantseva VV, Koroleva PI, Gilep AA, Napolskii KS, Ivanov YD, Kanashenko SL, Archakov AI. Shumyantseva VV, et al. Among authors: gilep aa. Dokl Biochem Biophys. 2022 Oct;506(1):215-219. doi: 10.1134/S1607672922050131. Epub 2022 Oct 27. Dokl Biochem Biophys. 2022. PMID: 36303055

3

Improving the Efficiency of Electrocatalysis of Cytochrome P450 3A4 by Modifying the Electrode with Membrane Protein Streptolysin O for Studying the Metabolic Transformations of Drugs.

Koroleva PI, Gilep AA, Kraevsky SV, Tsybruk TV, Shumyantseva VV. Koroleva PI, et al. Among authors: gilep aa. Biosensors (Basel). 2023 Apr 4;13(4):457. doi: 10.3390/bios13040457. Biosensors (Basel). 2023. PMID: 37185532 Free PMC article.

4

Molecular Cloning, Heterologous Expression, Purification, and Evaluation of Protein-Ligand Interactions of CYP51 of Candida krusei Azole-Resistant Fungal Strain.

Tsybruk TV, Kaluzhskiy LA, Mezentsev YV, Makarieva TN, Tabakmaher KM, Ivanchina NV, Dmitrenok PS, Baranovsky AV, Gilep AA, Ivanov AS. Tsybruk TV, et al. Among authors: gilep aa. Biomedicines. 2023 Oct 24;11(11):2873. doi: 10.3390/biomedicines11112873. Biomedicines. 2023. PMID: 38001874 Free PMC article.

5

Site-directed mutagenesis of cytochrome P450scc (CYP11A1). Effect of lysine residue substitution on its structural and functional properties.

Lepesheva GI, Azeva TN, Strushkevich NV, Gilep AA, Usanov SA. Lepesheva GI, et al. Among authors: gilep aa. Biochemistry (Mosc). 2000 Dec;65(12):1409-18. doi: 10.1023/a:1002809024292. Biochemistry (Mosc). 2000. PMID: 11173513

6

Interaction of apo-cytochrome b5 with cytochromes P4503A4 and P45017A: relevance of heme transfer reactions.

Guryev OL, Gilep AA, Usanov SA, Estabrook RW. Guryev OL, et al. Among authors: gilep aa. Biochemistry. 2001 Apr 24;40(16):5018-31. doi: 10.1021/bi002305w. Biochemistry. 2001. PMID: 11305918

7

Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments.

Gilep AA, Guryev OL, Usanov SA, Estabrook RW. Gilep AA, et al. Arch Biochem Biophys. 2001 Jun 15;390(2):215-21. doi: 10.1006/abbi.2001.2372. Arch Biochem Biophys. 2001. PMID: 11396924

8

Expression, purification, and physical properties of recombinant flavocytochrome fusion proteins containing rat cytochrome b(5) linked to NADPH-cytochrome P450 reductase by different membrane-binding segments.

Gilep AA, Guryev OL, Usanov SA, Estabrook RW. Gilep AA, et al. Arch Biochem Biophys. 2001 Jun 15;390(2):222-34. doi: 10.1006/abbi.2001.2371. Arch Biochem Biophys. 2001. PMID: 11396925

9

Site-directed mutagenesis of cytochrome P450scc. II. Effect of replacement of the Arg425 and Arg426 residues on the structural and functional properties of the cytochrome P450scc.

Azeva TN, Gilep AA, Lepesheva GI, Strushkevich NV, Usanov SA. Azeva TN, et al. Among authors: gilep aa. Biochemistry (Mosc). 2001 May;66(5):564-75. doi: 10.1023/a:1010271205147. Biochemistry (Mosc). 2001. PMID: 11405894

10

An enzymatically active chimeric protein containing the hydrophilic form of NADPH-cytochrome P450 reductase fused to the membrane-binding domain of cytochrome b5.

Gilep AA, Guryev OL, Usanov SA, Estabrook RW. Gilep AA, et al. Biochem Biophys Res Commun. 2001 Jun 22;284(4):937-41. doi: 10.1006/bbrc.2001.5075. Biochem Biophys Res Commun. 2001. PMID: 11409883

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