Giles A - Search Results

1

T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma.

Woroniecka K, Chongsathidkiet P, Rhodin K, Kemeny H, Dechant C, Farber SH, Elsamadicy AA, Cui X, Koyama S, Jackson C, Hansen LJ, Johanns TM, Sanchez-Perez L, Chandramohan V, Yu YA, Bigner DD, Giles A, Healy P, Dranoff G, Weinhold KJ, Dunn GP, Fecci PE. Woroniecka K, et al. Among authors: giles a. Clin Cancer Res. 2018 Sep 1;24(17):4175-4186. doi: 10.1158/1078-0432.CCR-17-1846. Epub 2018 Feb 7. Clin Cancer Res. 2018. PMID: 29437767 Free PMC article.

2

Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy.

Giles AJ, Hutchinson MND, Sonnemann HM, Jung J, Fecci PE, Ratnam NM, Zhang W, Song H, Bailey R, Davis D, Reid CM, Park DM, Gilbert MR. Giles AJ, et al. J Immunother Cancer. 2018 Jun 11;6(1):51. doi: 10.1186/s40425-018-0371-5. J Immunother Cancer. 2018. PMID: 29891009 Free PMC article.

3

Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma.

Jung J, Zhang Y, Celiku O, Zhang W, Song H, Williams BJ, Giles AJ, Rich JN, Abounader R, Gilbert MR, Park DM. Jung J, et al. Cancer Res. 2019 Oct 15;79(20):5218-5232. doi: 10.1158/0008-5472.CAN-19-0198. Epub 2019 Sep 5. Cancer Res. 2019. PMID: 31488423 Free PMC article.

4

Hypoxia in the glioblastoma microenvironment: shaping the phenotype of cancer stem-like cells.

Colwell N, Larion M, Giles AJ, Seldomridge AN, Sizdahkhani S, Gilbert MR, Park DM. Colwell N, et al. Neuro Oncol. 2017 Jul 1;19(7):887-896. doi: 10.1093/neuonc/now258. Neuro Oncol. 2017. PMID: 28339582 Free PMC article. Review.

5

Physiological, Tumor, and Metastatic Niches: Opportunities and Challenges for Targeting the Tumor Microenvironment.

Murgai M, Giles A, Kaplan R. Murgai M, et al. Among authors: giles a. Crit Rev Oncog. 2015;20(3-4):301-14. doi: 10.1615/critrevoncog.2015013668. Crit Rev Oncog. 2015. PMID: 26349421 Free PMC article. Review.

6

Immunotherapy in CNS cancers: the role of immune cell trafficking.

Ratnam NM, Gilbert MR, Giles AJ. Ratnam NM, et al. Neuro Oncol. 2019 Jan 1;21(1):37-46. doi: 10.1093/neuonc/noy084. Neuro Oncol. 2019. PMID: 29771386 Free PMC article. Review.

7

Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade.

Lynes J, Jackson S, Sanchez V, Dominah G, Wang X, Kuek A, Hayes CP, Benzo S, Scott GC, Chittiboina P, Zaghloul KA, Park DM, Wu J, Hourigan CS, Giles AJ, Wu T, Maric D, Chen J, Quezado M, Heiss JD, Gilbert MR, Nduom EK. Lynes J, et al. Among authors: giles aj. Neurosurgery. 2019 Apr 1;84(4):945-953. doi: 10.1093/neuros/nyy392. Neurosurgery. 2019. PMID: 30189044 Free PMC article. Clinical Trial.

8

T lymphocyte-targeted immune checkpoint modulation in glioma.

Kelly WJ, Giles AJ, Gilbert M. Kelly WJ, et al. J Immunother Cancer. 2020 Feb;8(1):e000379. doi: 10.1136/jitc-2019-000379. J Immunother Cancer. 2020. PMID: 32051289 Free PMC article. Review.

9

Programmed Death Ligand 1 Is a Negative Prognostic Marker in Recurrent Isocitrate Dehydrogenase-Wildtype Glioblastoma.

Pratt D, Dominah G, Lobel G, Obungu A, Lynes J, Sanchez V, Adamstein N, Wang X, Edwards NA, Wu T, Maric D, Giles AJ, Gilbert MR, Quezado M, Nduom EK. Pratt D, et al. Among authors: giles aj. Neurosurgery. 2019 Aug 1;85(2):280-289. doi: 10.1093/neuros/nyy268. Neurosurgery. 2019. PMID: 30011045 Free PMC article.

10

Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy.

Highfill SL, Cui Y, Giles AJ, Smith JP, Zhang H, Morse E, Kaplan RN, Mackall CL. Highfill SL, et al. Sci Transl Med. 2014 May 21;6(237):237ra67. doi: 10.1126/scitranslmed.3007974. Sci Transl Med. 2014. PMID: 24848257 Free PMC article.

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