Gillam EM - Search Results

1

Association of CYP1B1 genetic polymorphism with incidence to breast and lung cancer.

Watanabe J, Shimada T, Gillam EM, Ikuta T, Suemasu K, Higashi Y, Gotoh O, Kawajiri K. Watanabe J, et al. Among authors: gillam em. Pharmacogenetics. 2000 Feb;10(1):25-33. doi: 10.1097/00008571-200002000-00004. Pharmacogenetics. 2000. PMID: 10739169

2

Catalytic properties of polymorphic human cytochrome P450 1B1 variants.

Shimada T, Watanabe J, Kawajiri K, Sutter TR, Guengerich FP, Gillam EM, Inoue K. Shimada T, et al. Among authors: gillam em. Carcinogenesis. 1999 Aug;20(8):1607-13. doi: 10.1093/carcin/20.8.1607. Carcinogenesis. 1999. PMID: 10426814

3

Specificity of 17beta-oestradiol and benzo[a]pyrene oxidation by polymorphic human cytochrome P4501B1 variants substituted at residues 48, 119 and 432.

Shimada T, Watanabe J, Inoue K, Guengerich FP, Gillam EM. Shimada T, et al. Among authors: gillam em. Xenobiotica. 2001 Mar;31(3):163-76. doi: 10.1080/00498250110043490. Xenobiotica. 2001. PMID: 11465393

4

Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009.

Shimada T, Oda Y, Gillam EM, Guengerich FP, Inoue K. Shimada T, et al. Among authors: gillam em. Drug Metab Dispos. 2001 Sep;29(9):1176-82. Drug Metab Dispos. 2001. PMID: 11502724

5

Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.

Shimada T, Gillam EM, Oda Y, Tsumura F, Sutter TR, Guengerich FP, Inoue K. Shimada T, et al. Among authors: gillam em. Chem Res Toxicol. 1999 Jul;12(7):623-9. doi: 10.1021/tx990028s. Chem Res Toxicol. 1999. PMID: 10409402

6

Roles of NADPH-P450 reductase in the O-deethylation of 7-ethoxycoumarin by recombinant human cytochrome P450 1B1 variants in Escherichia coli.

Shimada T, Tsumura F, Gillam EM, Guengerich FP, Inoue K. Shimada T, et al. Among authors: gillam em. Protein Expr Purif. 2000 Oct;20(1):73-80. doi: 10.1006/prep.2000.1302. Protein Expr Purif. 2000. PMID: 11035953

7

Oxidation of xenobiotics by recombinant human cytochrome P450 1B1.

Shimada T, Gillam EM, Sutter TR, Strickland PT, Guengerich FP, Yamazaki H. Shimada T, et al. Among authors: gillam em. Drug Metab Dispos. 1997 May;25(5):617-22. Drug Metab Dispos. 1997. PMID: 9152602

8

Molecular modelling of human CYP1B1 substrate interactions and investigation of allelic variant effects on metabolism.

Lewis DF, Gillam EM, Everett SA, Shimada T. Lewis DF, et al. Among authors: gillam em. Chem Biol Interact. 2003 Jun 15;145(3):281-95. doi: 10.1016/s0009-2797(03)00021-8. Chem Biol Interact. 2003. PMID: 12732455

9

Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.

Oda Y, Aryal P, Terashita T, Gillam EM, Guengerich FP, Shimada T. Oda Y, et al. Among authors: gillam em. Mutat Res. 2001 May 31;492(1-2):81-90. doi: 10.1016/s1383-5718(01)00154-1. Mutat Res. 2001. PMID: 11377247

10

Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies.

Peter Guengerich F, Chun YJ, Kim D, Gillam EM, Shimada T. Peter Guengerich F, et al. Among authors: gillam em. Mutat Res. 2003 Feb-Mar;523-524:173-82. doi: 10.1016/s0027-5107(02)00333-0. Mutat Res. 2003. PMID: 12628515 Review.

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