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Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor.
Dunn C, Wiltshire C, MacLaren A, Gillespie DA. Dunn C, et al. Among authors: gillespie da. Cell Signal. 2002 Jul;14(7):585-93. doi: 10.1016/s0898-6568(01)00275-3. Cell Signal. 2002. PMID: 11955951 Review.
c-Jun-deficient cells undergo premature senescence as a result of spontaneous DNA damage accumulation.
MacLaren A, Black EJ, Clark W, Gillespie DA. MacLaren A, et al. Among authors: gillespie da. Mol Cell Biol. 2004 Oct;24(20):9006-18. doi: 10.1128/MCB.24.20.9006-9018.2004. Mol Cell Biol. 2004. PMID: 15456874 Free PMC article.
Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX.
Mac Partlin M, Homer E, Robinson H, McCormick CJ, Crouch DH, Durant ST, Matheson EC, Hall AG, Gillespie DA, Brown R. Mac Partlin M, et al. Among authors: gillespie da. Oncogene. 2003 Feb 13;22(6):819-25. doi: 10.1038/sj.onc.1206252. Oncogene. 2003. PMID: 12584560
Analysing the DNA damage and replication checkpoints in DT40 cells.
Rainey MD, Zachos G, Gillespie DA. Rainey MD, et al. Among authors: gillespie da. Subcell Biochem. 2006;40:107-17. doi: 10.1007/978-1-4020-4896-8_8. Subcell Biochem. 2006. PMID: 17623903 Review.
Invasion of normal human fibroblasts induced by v-Fos is independent of proliferation, immortalization, and the tumor suppressors p16INK4a and p53.
Scott LA, Vass JK, Parkinson EK, Gillespie DA, Winnie JN, Ozanne BW. Scott LA, et al. Among authors: gillespie da. Mol Cell Biol. 2004 Feb;24(4):1540-59. doi: 10.1128/mcb.24.4.1540-1559.2004. Mol Cell Biol. 2004. PMID: 14749371 Free PMC article.
Estrogen receptor activation function 2 (AF-2) is essential for hormone-dependent transactivation and cell transformation induced by a v-Jun DNA binding domain-estrogen receptor chimera.
Dunn CA, Clark W, Black EJ, Gillespie DA. Dunn CA, et al. Among authors: gillespie da. Biochim Biophys Acta. 2003 Aug 25;1628(3):147-55. doi: 10.1016/s0167-4781(03)00136-2. Biochim Biophys Acta. 2003. PMID: 12932827
Cell transformation by v-Jun deactivates ERK MAP kinase signalling.
Black EJ, Walker M, Clark W, MacLaren A, Gillespie DA. Black EJ, et al. Among authors: gillespie da. Oncogene. 2002 Sep 19;21(42):6540-8. doi: 10.1038/sj.onc.1205851. Oncogene. 2002. PMID: 12226757
A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria.
Wiltshire C, Matsushita M, Tsukada S, Gillespie DA, May GH. Wiltshire C, et al. Among authors: gillespie da. Biochem J. 2002 Nov 1;367(Pt 3):577-85. doi: 10.1042/BJ20020553. Biochem J. 2002. PMID: 12167088 Free PMC article.
The BRCA2 transactivation domain does not interact with JNK.
May GH, Harris F, Gillespie D, Black DM. May GH, et al. Genes Chromosomes Cancer. 1999 Aug;25(4):407-9. doi: 10.1002/(sici)1098-2264(199908)25:4<407::aid-gcc16>;2-i. Genes Chromosomes Cancer. 1999. PMID: 10398438
Sab (SH3BP5), a novel mitochondria-localized JNK-interacting protein.
Wiltshire C, Gillespie DA, May GH. Wiltshire C, et al. Among authors: gillespie da. Biochem Soc Trans. 2004 Dec;32(Pt 6):1075-7. doi: 10.1042/BST0321075. Biochem Soc Trans. 2004. PMID: 15506969
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