Gilliland DG - Search Results

1

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Kelly L, Shigematsu H, Johnson L, Akashi K, Tuveson DA, Jacks T, Gilliland DG. Chan IT, et al. Among authors: gilliland dg. J Clin Invest. 2004 Feb;113(4):528-38. doi: 10.1172/JCI20476. J Clin Invest. 2004. PMID: 14966562 Free PMC article.

2

Oncogenic K-ras in mouse models of myeloproliferative disease and acute myeloid leukemia.

Chan IT, Gilliland DG. Chan IT, et al. Among authors: gilliland dg. Cell Cycle. 2004 May;3(5):536-7. doi: 10.4161/cc.3.5.828. Epub 2004 May 5. Cell Cycle. 2004. PMID: 15020845

3

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

Growney JD, Shigematsu H, Li Z, Lee BH, Adelsperger J, Rowan R, Curley DP, Kutok JL, Akashi K, Williams IR, Speck NA, Gilliland DG. Growney JD, et al. Among authors: gilliland dg. Blood. 2005 Jul 15;106(2):494-504. doi: 10.1182/blood-2004-08-3280. Epub 2005 Mar 22. Blood. 2005. PMID: 15784726 Free PMC article.

4

Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Moore S, Shigematsu H, Ley TJ, Akashi K, Le Beau MM, Gilliland DG. Chan IT, et al. Among authors: gilliland dg. Blood. 2006 Sep 1;108(5):1708-15. doi: 10.1182/blood-2006-04-015040. Epub 2006 May 4. Blood. 2006. PMID: 16675706 Free PMC article.

5

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.

Mercher T, Raffel GD, Moore SA, Cornejo MG, Baudry-Bluteau D, Cagnard N, Jesneck JL, Pikman Y, Cullen D, Williams IR, Akashi K, Shigematsu H, Bourquin JP, Giovannini M, Vainchenker W, Levine RL, Lee BH, Bernard OA, Gilliland DG. Mercher T, et al. Among authors: gilliland dg. J Clin Invest. 2009 Apr;119(4):852-64. doi: 10.1172/JCI35901. Epub 2009 Mar 16. J Clin Invest. 2009. PMID: 19287095 Free PMC article.

6

FGFR3 as a therapeutic target of the small molecule inhibitor PKC412 in hematopoietic malignancies.

Chen J, Lee BH, Williams IR, Kutok JL, Mitsiades CS, Duclos N, Cohen S, Adelsperger J, Okabe R, Coburn A, Moore S, Huntly BJ, Fabbro D, Anderson KC, Griffin JD, Gilliland DG. Chen J, et al. Among authors: gilliland dg. Oncogene. 2005 Dec 15;24(56):8259-67. doi: 10.1038/sj.onc.1208989. Oncogene. 2005. PMID: 16091734

7

FLT3 internal tandem duplication mutations induce myeloproliferative or lymphoid disease in a transgenic mouse model.

Lee BH, Williams IR, Anastasiadou E, Boulton CL, Joseph SW, Amaral SM, Curley DP, Duclos N, Huntly BJ, Fabbro D, Griffin JD, Gilliland DG. Lee BH, et al. Among authors: gilliland dg. Oncogene. 2005 Nov 24;24(53):7882-92. doi: 10.1038/sj.onc.1208933. Oncogene. 2005. PMID: 16116483

8

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model.

Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG. Kelly LM, et al. Among authors: gilliland dg. Blood. 2002 Jan 1;99(1):310-8. doi: 10.1182/blood.v99.1.310. Blood. 2002. PMID: 11756186 Free article.

9

A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9.

Dash AB, Williams IR, Kutok JL, Tomasson MH, Anastasiadou E, Lindahl K, Li S, Van Etten RA, Borrow J, Housman D, Druker B, Gilliland DG. Dash AB, et al. Among authors: gilliland dg. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7622-7. doi: 10.1073/pnas.102583199. Proc Natl Acad Sci U S A. 2002. PMID: 12032333 Free PMC article.

10

PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model.

Kelly LM, Kutok JL, Williams IR, Boulton CL, Amaral SM, Curley DP, Ley TJ, Gilliland DG. Kelly LM, et al. Among authors: gilliland dg. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8283-8. doi: 10.1073/pnas.122233699. Proc Natl Acad Sci U S A. 2002. PMID: 12060771 Free PMC article.

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