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Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders.
Levine RL, Pardanani A, Tefferi A, Gilliland DG. Levine RL, et al. Among authors: gilliland dg. Nat Rev Cancer. 2007 Sep;7(9):673-83. doi: 10.1038/nrc2210. Nat Rev Cancer. 2007. PMID: 17721432 Review.
Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.
Schwaller J, Parganas E, Wang D, Cain D, Aster JC, Williams IR, Lee CK, Gerthner R, Kitamura T, Frantsve J, Anastasiadou E, Loh ML, Levy DE, Ihle JN, Gilliland DG. Schwaller J, et al. Among authors: gilliland dg. Mol Cell. 2000 Sep;6(3):693-704. doi: 10.1016/s1097-2765(00)00067-8. Mol Cell. 2000. PMID: 11030348
Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation.
Frantsve J, Schwaller J, Sternberg DW, Kutok J, Gilliland DG. Frantsve J, et al. Among authors: gilliland dg. Mol Cell Biol. 2001 May;21(10):3547-57. doi: 10.1128/MCB.21.10.3547-3557.2001. Mol Cell Biol. 2001. PMID: 11313480 Free PMC article.
The diverse role of the ETS family of transcription factors in cancer.
Gilliland DG. Gilliland DG. Clin Cancer Res. 2001 Mar;7(3):451-3. Clin Cancer Res. 2001. PMID: 11297232 No abstract available.
Intensified therapy for infants with acute lymphoblastic leukemia: results from the Dana-Farber Cancer Institute Consortium.
Silverman LB, McLean TW, Gelber RD, Donnelly MJ, Gilliland DG, Tarbell NJ, Sallan SE. Silverman LB, et al. Among authors: gilliland dg. Cancer. 1997 Dec 15;80(12):2285-95. Cancer. 1997. PMID: 9404706 Clinical Trial.
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.
Schwaller J, Frantsve J, Aster J, Williams IR, Tomasson MH, Ross TS, Peeters P, Van Rompaey L, Van Etten RA, Ilaria R Jr, Marynen P, Gilliland DG. Schwaller J, et al. Among authors: gilliland dg. EMBO J. 1998 Sep 15;17(18):5321-33. doi: 10.1093/emboj/17.18.5321. EMBO J. 1998. PMID: 9736611 Free PMC article.
Bone marrow dysplasia in patients with newly diagnosed acute myelogenous leukemia does not correlate with history of myelodysplasia or with remission rate and survival.
Ballen KK, Gilliland DG, Kalish LA, Shulman LN. Ballen KK, et al. Among authors: gilliland dg. Cancer. 1994 Jan 15;73(2):314-21. doi: 10.1002/1097-0142(19940115)73:2<314::aid-cncr2820730214>3.0.co;2-c. Cancer. 1994. PMID: 8293394
Induction of myeloproliferative disease in mice by tyrosine kinase fusion oncogenes does not require granulocyte-macrophage colony-stimulating factor or interleukin-3.
Tomasson MH, Williams IR, Li S, Kutok J, Cain D, Gillessen S, Dranoff G, Van Etten RA, Gilliland DG. Tomasson MH, et al. Among authors: gilliland dg. Blood. 2001 Mar 1;97(5):1435-41. doi: 10.1182/blood.v97.5.1435. Blood. 2001. PMID: 11222391
Interleukin 3 and granulocyte-macrophage colony-stimulating factor are not required for induction of chronic myeloid leukemia-like myeloproliferative disease in mice by BCR/ABL.
Li S, Gillessen S, Tomasson MH, Dranoff G, Gilliland DG, Van Etten RA. Li S, et al. Among authors: gilliland dg. Blood. 2001 Mar 1;97(5):1442-50. doi: 10.1182/blood.v97.5.1442. Blood. 2001. PMID: 11222392
TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor.
Tomasson MH, Williams IR, Hasserjian R, Udomsakdi C, McGrath SM, Schwaller J, Druker B, Gilliland DG. Tomasson MH, et al. Among authors: gilliland dg. Blood. 1999 Mar 1;93(5):1707-14. Blood. 1999. PMID: 10029600
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