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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways.
Carroll M, Tomasson MH, Barker GF, Golub TR, Gilliland DG. Carroll M, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14845-50. doi: 10.1073/pnas.93.25.14845. Proc Natl Acad Sci U S A. 1996. PMID: 8962143 Free PMC article.
Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia.
Ballen KK, Gilliland DG, Guinan EC, Hsieh CC, Parsons SK, Rimm IJ, Ferrara JL, Bierer BE, Weinstein HJ, Antin JH. Ballen KK, et al. Bone Marrow Transplant. 1997 Nov;20(9):737-43. doi: 10.1038/sj.bmt.1700971. Bone Marrow Transplant. 1997. PMID: 9384475 Clinical Trial.
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.
Schwaller J, Frantsve J, Aster J, Williams IR, Tomasson MH, Ross TS, Peeters P, Van Rompaey L, Van Etten RA, Ilaria R Jr, Marynen P, Gilliland DG. Schwaller J, et al. EMBO J. 1998 Sep 15;17(18):5321-33. doi: 10.1093/emboj/17.18.5321. EMBO J. 1998. PMID: 9736611 Free PMC article.
Induction of myeloproliferative disease in mice by tyrosine kinase fusion oncogenes does not require granulocyte-macrophage colony-stimulating factor or interleukin-3.
Tomasson MH, Williams IR, Li S, Kutok J, Cain D, Gillessen S, Dranoff G, Van Etten RA, Gilliland DG. Tomasson MH, et al. Blood. 2001 Mar 1;97(5):1435-41. doi: 10.1182/blood.v97.5.1435. Blood. 2001. PMID: 11222391
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
Golub TR, Barker GF, Bohlander SK, Hiebert SW, Ward DC, Bray-Ward P, Morgan E, Raimondi SC, Rowley JD, Gilliland DG. Golub TR, et al. Proc Natl Acad Sci U S A. 1995 May 23;92(11):4917-21. doi: 10.1073/pnas.92.11.4917. Proc Natl Acad Sci U S A. 1995. PMID: 7761424 Free PMC article.
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