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ON 01910.Na (rigosertib) inhibits PI3K/Akt pathway and activates oxidative stress signals in head and neck cancer cell lines.
Prasad A, Khudaynazar N, Tantravahi RV, Gillum AM, Hoffman BS. Prasad A, et al. Among authors: gillum am. Oncotarget. 2016 Nov 29;7(48):79388-79400. doi: 10.18632/oncotarget.12692. Oncotarget. 2016. PMID: 27764820 Free PMC article.
Combined administration of rituximab and on 013105 induces apoptosis in mantle cell lymphoma cells and reduces tumor burden in a mouse model of mantle cell lymphoma.
Prasad A, Shrivastava A, Papadopoulos E, Kuzontkoski PM, Reddy MV, Gillum AM, Kumar R, Reddy EP, Groopman JE. Prasad A, et al. Among authors: gillum am. Clin Cancer Res. 2013 Jan 1;19(1):85-95. doi: 10.1158/1078-0432.CCR-12-1425. Epub 2012 Nov 1. Clin Cancer Res. 2013. PMID: 23124440 Free article.
Effects of formulation and route of administration on the systemic availability of Ex-RAD®, a new radioprotectant, in preclinical species.
Chun AW, Freshwater RE, Taft DR, Gillum AM, Maniar M. Chun AW, et al. Among authors: gillum am. Biopharm Drug Dispos. 2011 Mar;32(2):99-111. doi: 10.1002/bdd.741. Epub 2011 Jan 14. Biopharm Drug Dispos. 2011. PMID: 21341279
Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O6-alkylguanine-DNA alkyltransferase.
Barvaux VA, Lorigan P, Ranson M, Gillum AM, McElhinney RS, McMurry TB, Margison GP. Barvaux VA, et al. Among authors: gillum am. Mol Cancer Ther. 2004 Oct;3(10):1215-20. Mol Cancer Ther. 2004. PMID: 15486188 Free article.
Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment.
Klasa RJ, Gillum AM, Klem RE, Frankel SR. Klasa RJ, et al. Among authors: gillum am. Antisense Nucleic Acid Drug Dev. 2002 Jun;12(3):193-213. doi: 10.1089/108729002760220798. Antisense Nucleic Acid Drug Dev. 2002. PMID: 12162702 Review.
Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp.
Barrow CJ, Oleynek JJ, Marinelli V, Sun HH, Kaplita P, Sedlock DM, Gillum AM, Chadwick CC, Cooper R. Barrow CJ, et al. Among authors: gillum am. J Antibiot (Tokyo). 1997 Sep;50(9):729-33. doi: 10.7164/antibiotics.50.729. J Antibiot (Tokyo). 1997. PMID: 9360616 Free article.
Phevalin, a new calpain inhibitor, from a Streptomyces sp.
Alvarez ME, White CB, Gregory J, Kydd GC, Harris A, Sun HH, Gillum AM, Cooper R. Alvarez ME, et al. Among authors: gillum am. J Antibiot (Tokyo). 1995 Oct;48(10):1165-7. doi: 10.7164/antibiotics.48.1165. J Antibiot (Tokyo). 1995. PMID: 7490226 Free article. No abstract available.
Isolation and structure elucidation of two new calpain inhibitors from Streptomyces griseus.
Alvarez ME, Houck DR, White CB, Brownell JE, Bobko MA, Rodger CA, Stawicki MB, Sun HH, Gillum AM, Cooper R. Alvarez ME, et al. Among authors: gillum am. J Antibiot (Tokyo). 1994 Nov;47(11):1195-201. doi: 10.7164/antibiotics.47.1195. J Antibiot (Tokyo). 1994. PMID: 8002381 Free article.
Cucurbitacins, cell adhesion inhibitors from Conobea scoparioides.
Musza LL, Speight P, McElhiney S, Barrow CJ, Gillum AM, Cooper R, Killar LM. Musza LL, et al. Among authors: gillum am. J Nat Prod. 1994 Nov;57(11):1498-502. doi: 10.1021/np50113a004. J Nat Prod. 1994. PMID: 7852999
WIN 66306, a new neurokinin antagonist produced by an Aspergillus species: fermentation, isolation and physico-chemical properties.
Barrow CJ, Sedlock DM, Sun HH, Cooper R, Gillum AM. Barrow CJ, et al. Among authors: gillum am. J Antibiot (Tokyo). 1994 Nov;47(11):1182-7. doi: 10.7164/antibiotics.47.1182. J Antibiot (Tokyo). 1994. PMID: 7528191 Free article.
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