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Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR. Coleman DE, et al. Science. 1994 Sep 2;265(5177):1405-12. doi: 10.1126/science.8073283. Science. 1994. PMID: 8073283
Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis.
Mixon MB, Lee E, Coleman DE, Berghuis AM, Gilman AG, Sprang SR. Mixon MB, et al. Science. 1995 Nov 10;270(5238):954-60. doi: 10.1126/science.270.5238.954. Science. 1995. PMID: 7481799
Receptor regulation of G-protein palmitoylation.
Mumby SM, Kleuss C, Gilman AG. Mumby SM, et al. Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2800-4. doi: 10.1073/pnas.91.7.2800. Proc Natl Acad Sci U S A. 1994. PMID: 8146194 Free PMC article.
Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.
Gibson SK, Gilman AG. Gibson SK, et al. Among authors: gilman ag. Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):212-7. doi: 10.1073/pnas.0509763102. Epub 2005 Dec 21. Proc Natl Acad Sci U S A. 2006. PMID: 16371464 Free PMC article.
TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors.
Chen Z, Raman M, Chen L, Lee SF, Gilman AG, Cobb MH. Chen Z, et al. Among authors: gilman ag. J Biol Chem. 2003 Jun 20;278(25):22278-83. doi: 10.1074/jbc.M301173200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665513 Free article.
Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins.
Krumins AM, Gilman AG. Krumins AM, et al. Among authors: gilman ag. J Biol Chem. 2006 Apr 14;281(15):10250-62. doi: 10.1074/jbc.M511551200. Epub 2006 Jan 30. J Biol Chem. 2006. PMID: 16446365 Free article.
Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes.
Tall GG, Gilman AG. Tall GG, et al. Among authors: gilman ag. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16584-9. doi: 10.1073/pnas.0508306102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275912 Free PMC article.
Allosteric determinants in guanine nucleotide-binding proteins.
Hatley ME, Lockless SW, Gibson SK, Gilman AG, Ranganathan R. Hatley ME, et al. Among authors: gilman ag. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14445-50. doi: 10.1073/pnas.1835919100. Epub 2003 Nov 17. Proc Natl Acad Sci U S A. 2003. PMID: 14623969 Free PMC article.
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