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A variable residue in the pore of Kv1 channels is critical for the high affinity of blockers from sea anemones and scorpions.
Gilquin B, Braud S, Eriksson MA, Roux B, Bailey TD, Priest BT, Garcia ML, Ménez A, Gasparini S. Gilquin B, et al. J Biol Chem. 2005 Jul 22;280(29):27093-102. doi: 10.1074/jbc.M413626200. Epub 2005 May 12. J Biol Chem. 2005. PMID: 15890656 Free article.
To address this issue we refined our previous three-dimensional models of the complex between the sea anemone toxin BgK and the S5-S6 region of Kv1.1 (Gilquin, B., Racape, J., Wrisch, A., Visan, V., Lecoq, A., Grissmer, S., Menez, A., and Gasparini, S. (2002) J. ...
To address this issue we refined our previous three-dimensional models of the complex between the sea anemone toxin BgK and the S5-S6 region …
Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor.
Marquer C, Fruchart-Gaillard C, Letellier G, Marcon E, Mourier G, Zinn-Justin S, Ménez A, Servent D, Gilquin B. Marquer C, et al. Among authors: gilquin b. J Biol Chem. 2011 Sep 9;286(36):31661-75. doi: 10.1074/jbc.M111.261404. Epub 2011 Jun 17. J Biol Chem. 2011. PMID: 21685390 Free PMC article.
96 results