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96 results
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Inflammatory resolution: new opportunities for drug discovery.
Gilroy DW, Lawrence T, Perretti M, Rossi AG. Gilroy DW, et al. Nat Rev Drug Discov. 2004 May;3(5):401-16. doi: 10.1038/nrd1383. Nat Rev Drug Discov. 2004. PMID: 15136788 Review. No abstract available.
Different glucocorticoids vary in their genomic and non-genomic mechanism of action in A549 cells.
Croxtall JD, van Hal PT, Choudhury Q, Gilroy DW, Flower RJ. Croxtall JD, et al. Among authors: gilroy dw. Br J Pharmacol. 2002 Jan;135(2):511-9. doi: 10.1038/sj.bjp.0704474. Br J Pharmacol. 2002. PMID: 11815387 Free PMC article.
Anti-inflammatory lipid mediators and insights into the resolution of inflammation.
Lawrence T, Willoughby DA, Gilroy DW. Lawrence T, et al. Among authors: gilroy dw. Nat Rev Immunol. 2002 Oct;2(10):787-95. doi: 10.1038/nri915. Nat Rev Immunol. 2002. PMID: 12360216 Review.
Attenuation of glucocorticoid functions in an Anx-A1-/- cell line.
Croxtall JD, Gilroy DW, Solito E, Choudhury Q, Ward BJ, Buckingham JC, Flower RJ. Croxtall JD, et al. Among authors: gilroy dw. Biochem J. 2003 May 1;371(Pt 3):927-35. doi: 10.1042/BJ20021856. Biochem J. 2003. PMID: 12553880 Free PMC article.
Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis.
Gilroy DW, Colville-Nash PR, McMaster S, Sawatzky DA, Willoughby DA, Lawrence T. Gilroy DW, et al. FASEB J. 2003 Dec;17(15):2269-71. doi: 10.1096/fj.02-1162fje. Epub 2003 Oct 16. FASEB J. 2003. PMID: 14563690
A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation.
Gilroy DW, Newson J, Sawmynaden P, Willoughby DA, Croxtall JD. Gilroy DW, et al. FASEB J. 2004 Mar;18(3):489-98. doi: 10.1096/fj.03-0837com. FASEB J. 2004. PMID: 15003994
15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation.
Paul-Clark MJ, Van Cao T, Moradi-Bidhendi N, Cooper D, Gilroy DW. Paul-Clark MJ, et al. Among authors: gilroy dw. J Exp Med. 2004 Jul 5;200(1):69-78. doi: 10.1084/jem.20040566. J Exp Med. 2004. PMID: 15238606 Free PMC article.
Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkappaBalpha repressor.
Blackwell NM, Sembi P, Newson JS, Lawrence T, Gilroy DW, Kabouridis PS. Blackwell NM, et al. Among authors: gilroy dw. Arthritis Rheum. 2004 Aug;50(8):2675-84. doi: 10.1002/art.20467. Arthritis Rheum. 2004. PMID: 15334484 Free PMC article.
Aspirin and steroids: new mechanistic findings and avenues for drug discovery.
Gilroy DW, Perretti M. Gilroy DW, et al. Curr Opin Pharmacol. 2005 Aug;5(4):405-11. doi: 10.1016/j.coph.2005.02.006. Curr Opin Pharmacol. 2005. PMID: 15955733 Review.
New insights into the anti-inflammatory actions of aspirin-induction of nitric oxide through the generation of epi-lipoxins.
Gilroy DW. Gilroy DW. Mem Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:49-54. doi: 10.1590/s0074-02762005000900009. Epub 2005 Jun 14. Mem Inst Oswaldo Cruz. 2005. PMID: 15962098 Review.
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