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Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.
Gingras AC, Svitkin Y, Belsham GJ, Pause A, Sonenberg N. Gingras AC, et al. Proc Natl Acad Sci U S A. 1996 May 28;93(11):5578-83. doi: 10.1073/pnas.93.11.5578. Proc Natl Acad Sci U S A. 1996. PMID: 8643618 Free PMC article.
Phosphorylation of eIF-4E on serine 209 by protein kinase C is inhibited by the translational repressors, 4E-binding proteins.
Whalen SG, Gingras AC, Amankwa L, Mader S, Branton PE, Aebersold R, Sonenberg N. Whalen SG, et al. Among authors: gingras ac. J Biol Chem. 1996 May 17;271(20):11831-7. doi: 10.1074/jbc.271.20.11831. J Biol Chem. 1996. PMID: 8662663
The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth.
Rousseau D, Gingras AC, Pause A, Sonenberg N. Rousseau D, et al. Among authors: gingras ac. Oncogene. 1996 Dec 5;13(11):2415-20. Oncogene. 1996. PMID: 8957083
Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2.
Tsukiyama-Kohara K, Vidal SM, Gingras AC, Glover TW, Hanash SM, Heng H, Sonenberg N. Tsukiyama-Kohara K, et al. Among authors: gingras ac. Genomics. 1996 Dec 15;38(3):353-63. doi: 10.1006/geno.1996.0638. Genomics. 1996. PMID: 8975712
4E binding proteins inhibit the translation factor eIF4E without folded structure.
Fletcher CM, McGuire AM, Gingras AC, Li H, Matsuo H, Sonenberg N, Wagner G. Fletcher CM, et al. Among authors: gingras ac. Biochemistry. 1998 Jan 6;37(1):9-15. doi: 10.1021/bi972494r. Biochemistry. 1998. PMID: 9453748
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