Ginsburg D - Search Results

1

The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion.

Sharp AM, Stein PE, Pannu NS, Carrell RW, Berkenpas MB, Ginsburg D, Lawrence DA, Read RJ. Sharp AM, et al. Among authors: ginsburg d. Structure. 1999 Feb 15;7(2):111-8. doi: 10.1016/S0969-2126(99)80018-5. Structure. 1999. PMID: 10368279 Free article.

2

Localization of vitronectin binding domain in plasminogen activator inhibitor-1.

Lawrence DA, Berkenpas MB, Palaniappan S, Ginsburg D. Lawrence DA, et al. Among authors: ginsburg d. J Biol Chem. 1994 May 27;269(21):15223-8. J Biol Chem. 1994. PMID: 7515053 Free article.

3

Molecular evolution of plasminogen activator inhibitor-1 functional stability.

Berkenpas MB, Lawrence DA, Ginsburg D. Berkenpas MB, et al. Among authors: ginsburg d. EMBO J. 1995 Jul 3;14(13):2969-77. doi: 10.1002/j.1460-2075.1995.tb07299.x. EMBO J. 1995. PMID: 7621813 Free PMC article.

4

Engineering plasminogen activator inhibitor 1 mutants with increased functional stability.

Lawrence DA, Olson ST, Palaniappan S, Ginsburg D. Lawrence DA, et al. Among authors: ginsburg d. Biochemistry. 1994 Mar 29;33(12):3643-8. doi: 10.1021/bi00178a022. Biochemistry. 1994. PMID: 8142362

5

Characterization of the binding of different conformational forms of plasminogen activator inhibitor-1 to vitronectin. Implications for the regulation of pericellular proteolysis.

Lawrence DA, Palaniappan S, Stefansson S, Olson ST, Francis-Chmura AM, Shore JD, Ginsburg D. Lawrence DA, et al. Among authors: ginsburg d. J Biol Chem. 1997 Mar 21;272(12):7676-80. doi: 10.1074/jbc.272.12.7676. J Biol Chem. 1997. PMID: 9065424 Free article.

6

Deep mutational scanning of the plasminogen activator inhibitor-1 functional landscape.

Huttinger ZM, Haynes LM, Yee A, Kretz CA, Holding ML, Siemieniak DR, Lawrence DA, Ginsburg D. Huttinger ZM, et al. Among authors: ginsburg d. Sci Rep. 2021 Sep 22;11(1):18827. doi: 10.1038/s41598-021-97871-7. Sci Rep. 2021. PMID: 34552126 Free PMC article.

7

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates.

Lawrence DA, Ginsburg D, Day DE, Berkenpas MB, Verhamme IM, Kvassman JO, Shore JD. Lawrence DA, et al. Among authors: ginsburg d. J Biol Chem. 1995 Oct 27;270(43):25309-12. doi: 10.1074/jbc.270.43.25309. J Biol Chem. 1995. PMID: 7592687 Free article.

8

Kinetics of inactivation of alpha-thrombin by plasminogen activator inhibitor-1. Comparison of the effects of native and urea-treated forms of vitronectin.

Naski MC, Lawrence DA, Mosher DF, Podor TJ, Ginsburg D. Naski MC, et al. Among authors: ginsburg d. J Biol Chem. 1993 Jun 15;268(17):12367-72. J Biol Chem. 1993. PMID: 7685341 Free article.

9

Identification of tissue-type plasminogen activator-specific plasminogen activator inhibitor-1 mutants. Evidence that second sites of interaction contribute to target specificity.

Sherman PM, Lawrence DA, Verhamme IM, Paielli D, Shore JD, Ginsburg D. Sherman PM, et al. Among authors: ginsburg d. J Biol Chem. 1995 Apr 21;270(16):9301-6. doi: 10.1074/jbc.270.16.9301. J Biol Chem. 1995. PMID: 7721851 Free article.

Several PAI-1 variants that were inactive against uPA in a previous study (Sherman, P. M., Lawrence, D. A., Yang, A. Y., Vandenberg, E. T., Paielli, D., Olson, S. T., Shore, J. D., and Ginsburg, D. (1992) J. Biol. Chem. 267, 7588-7595) had signi …

Several PAI-1 variants that were inactive against uPA in a previous study (Sherman, P. M., Lawrence, D. A., Yang, A. Y., Vandenberg, …

10

Peptide-mediated inactivation of recombinant and platelet plasminogen activator inhibitor-1 in vitro.

Eitzman DT, Fay WP, Lawrence DA, Francis-Chmura AM, Shore JD, Olson ST, Ginsburg D. Eitzman DT, et al. Among authors: ginsburg d. J Clin Invest. 1995 May;95(5):2416-20. doi: 10.1172/JCI117937. J Clin Invest. 1995. PMID: 7738206 Free PMC article.

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