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103 results
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Page 1
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.
Cappelli A, Nannicini C, Gallelli A, Giuliani G, Valenti S, Mohr Gl, Anzini M, Mennuni L, Ferrari F, Caselli G, Giordani A, Peris W, Makovec F, Giorgi G, Vomero S. Cappelli A, et al. Among authors: giordani a. J Med Chem. 2008 Apr 10;51(7):2137-46. doi: 10.1021/jm7011563. Epub 2008 Mar 5. J Med Chem. 2008. PMID: 18318468
Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity.
Anzini M, Rovini M, Cappelli A, Vomero S, Manetti F, Botta M, Sautebin L, Rossi A, Pergola C, Ghelardini C, Norcini M, Giordani A, Makovec F, Anzellotti P, Patrignani P, Biava M. Anzini M, et al. Among authors: giordani a. J Med Chem. 2008 Aug 14;51(15):4476-81. doi: 10.1021/jm800084s. Epub 2008 Jul 4. J Med Chem. 2008. PMID: 18598017
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents.
Biava M, Porretta GC, Poce G, Supino S, Manetti F, Forli S, Botta M, Sautebin L, Rossi A, Pergola C, Ghelardini C, Norcini M, Makovec F, Giordani A, Anzellotti P, Cirilli R, Ferretti R, Gallinella B, La Torre F, Anzini M, Patrignani P. Biava M, et al. Among authors: giordani a. Bioorg Med Chem. 2008 Sep 1;16(17):8072-81. doi: 10.1016/j.bmc.2008.07.058. Epub 2008 Jul 24. Bioorg Med Chem. 2008. PMID: 18752957
Progress towards the identification of new aggrecanase inhibitors.
De Rienzo F, Saxena P, Filomia F, Caselli G, Colace F, Stasi L, Giordani A, Menziani MC. De Rienzo F, et al. Among authors: giordani a. Curr Med Chem. 2009;16(19):2395-415. doi: 10.2174/092986709788682092. Curr Med Chem. 2009. PMID: 19601788 Review.
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases.
Anzini M, Chelini A, Mancini A, Cappelli A, Frosini M, Ricci L, Valoti M, Magistretti J, Castelli L, Giordani A, Makovec F, Vomero S. Anzini M, et al. Among authors: giordani a. J Med Chem. 2010 Jan 28;53(2):734-44. doi: 10.1021/jm901375r. J Med Chem. 2010. PMID: 19950903
Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation.
Biava M, Porretta GC, Poce G, Battilocchio C, Manetti F, Botta M, Forli S, Sautebin L, Rossi A, Pergola C, Ghelardini C, Galeotti N, Makovec F, Giordani A, Anzellotti P, Patrignani P, Anzini M. Biava M, et al. Among authors: giordani a. J Med Chem. 2010 Jan 28;53(2):723-33. doi: 10.1021/jm901269y. J Med Chem. 2010. PMID: 19957931 Free article.
Enlarging the NSAIDs family: ether, ester and acid derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents.
Biava M, Porretta GC, Poce G, Battilocchio C, Botta M, Manetti F, Rovini M, Cappelli A, Sautebin L, Rossi A, Pergola C, Ghelardini C, Galeotti N, Makovec F, Giordani A, Anzellotti P, Tacconelli S, Patrignani P, Anzini M. Biava M, et al. Among authors: giordani a. Curr Med Chem. 2011;18(10):1540-54. doi: 10.2174/092986711795328364. Curr Med Chem. 2011. PMID: 21428878 Free article. Review.
103 results