Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

2,209 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
RB and cell cycle progression.
Giacinti C, Giordano A. Giacinti C, et al. Among authors: giordano a. Oncogene. 2006 Aug 28;25(38):5220-7. doi: 10.1038/sj.onc.1209615. Oncogene. 2006. PMID: 16936740 Review.
The Rb protein is a tumor suppressor, which plays a pivotal role in the negative control of the cell cycle and in tumor progression. ...Loss of pRb functions may induce cell cycle deregulation and so lead to a malignant phenotype. Gene inactivation of pRB thr …
The Rb protein is a tumor suppressor, which plays a pivotal role in the negative control of the cell cycle and in tumor progre …
Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: blocking p53-induced apoptosis unmasks G1 arrest.
Guillouf C, Graña X, Selvakumaran M, De Luca A, Giordano A, Hoffman B, Liebermann DA. Guillouf C, et al. Among authors: giordano a. Blood. 1995 May 15;85(10):2691-8. Blood. 1995. PMID: 7742528
Employing the myeloblastic leukemia M1 cell line, which does not express endogenous p53, and genetically engineered variants, it was recently shown that activation of p53, using a p53 temperature-sensitive mutant transgene (p53ts), resulted in rapid apoptosis that was dela …
Employing the myeloblastic leukemia M1 cell line, which does not express endogenous p53, and genetically engineered variants, it was recentl …
Modulation of retinoblastoma gene in normal adult hematopoiesis: peak expression and functional role in advanced erythroid differentiation.
Condorelli GL, Testa U, Valtieri M, Vitelli L, De Luca A, Barberi T, Montesoro E, Campisi S, Giordano A, Peschle C. Condorelli GL, et al. Among authors: giordano a. Proc Natl Acad Sci U S A. 1995 May 23;92(11):4808-12. doi: 10.1073/pnas.92.11.4808. Proc Natl Acad Sci U S A. 1995. PMID: 7761404 Free PMC article.
The retinoblastoma (RB) gene specifies a nuclear phosphoprotein (pRb 105), which is a prototype tumor suppressor inactivated in a variety of human tumors. ...Functional studies were performed by treatment of HPC differentiation culture with phosphorothioate a …
The retinoblastoma (RB) gene specifies a nuclear phosphoprotein (pRb 105), which is a prototype tumor suppressor inactivated i …
An E2F binding sequence negatively regulates the response of the insulin-like growth factor 1 (IGF-I) promoter to simian virus 40T antigen and to serum.
Porcu P, Graña X, Li S, Swantek J, De Luca A, Giordano A, Baserga R. Porcu P, et al. Among authors: giordano a. Oncogene. 1994 Aug;9(8):2125-34. Oncogene. 1994. PMID: 8035997
This short promoter contains an E2F binding site, that, in gel shifts, binds a protein complex, but only when the promoter activity is reduced or absent. ...By using antibodies in gel retardation analyses, we can show that the different protein complexes include, at least, …
This short promoter contains an E2F binding site, that, in gel shifts, binds a protein complex, but only when the promoter activity i …
Correlation between E2F-1 requirement in the S phase and E2F-1 transactivation of cell cycle-related genes in human cells.
Sala A, Nicolaides NC, Engelhard A, Bellon T, Lawe DC, Arnold A, Graña X, Giordano A, Calabretta B. Sala A, et al. Among authors: giordano a. Cancer Res. 1994 Mar 15;54(6):1402-6. Cancer Res. 1994. PMID: 8137237
Expression of the antisense transcripts during the G1-S transition resulted in a marked delay in the completion of DNA synthesis. ...These results suggest a major role for E2F-1 in the control of cell cycle progression via transcriptional regulation of proliferation …
Expression of the antisense transcripts during the G1-S transition resulted in a marked delay in the completion of DNA synthesis. ... …
Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain.
Mayol X, Graña X, Baldi A, Sang N, Hu Q, Giordano A. Mayol X, et al. Among authors: giordano a. Oncogene. 1993 Sep;8(9):2561-6. Oncogene. 1993. PMID: 8361765
The product of the retinoblastoma tumor suppressor gene (pRb) and p107 share a high degree of structural homology in the pocket region, which is thought to play a primary role in the function of these proteins. It is conceivable that there exists a larger fam …
The product of the retinoblastoma tumor suppressor gene (pRb) and p107 share a high degree of structural homology in the pocket regio …
Human p300 protein is a coactivator for the transcription factor MyoD.
Yuan W, Condorelli G, Caruso M, Felsani A, Giordano A. Yuan W, et al. Among authors: giordano a. J Biol Chem. 1996 Apr 12;271(15):9009-13. doi: 10.1074/jbc.271.15.9009. J Biol Chem. 1996. PMID: 8621548
Human p300 protein is a cellular target of adenoviral E1A oncoprotein and a potential transcriptional coactivator. Both p300 and Rb family protein-binding regions of E1A are required for the repression of muscle gene expression, which is regulated by MyoD family tra …
Human p300 protein is a cellular target of adenoviral E1A oncoprotein and a potential transcriptional coactivator. Both p300 a …
Genomic structure of the human retinoblastoma-related Rb2/p130 gene.
Baldi A, Boccia V, Claudio PP, De Luca A, Giordano A. Baldi A, et al. Among authors: giordano a. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4629-32. doi: 10.1073/pnas.93.10.4629. Proc Natl Acad Sci U S A. 1996. PMID: 8643454 Free PMC article.
The 5' flanking region revealed a structural organization characteristic of promoters of "housekeeping" and growth control-related genes. ...This study provides the molecular basis for understanding the transcriptional control of the Rb2/p130 gene and for implementing a
The 5' flanking region revealed a structural organization characteristic of promoters of "housekeeping" and growth control-related ge …
The retinoblastoma gene: its role in cell cycle and cancer.
Giordano A, Kaiser HE. Giordano A, et al. In Vivo. 1996 Mar-Apr;10(2):223-7. In Vivo. 1996. PMID: 8744804 Review.
However, it is difficult to rationalize the expression of pRb in a wide range of tissues with the fact that only limited cell types are susceptible to tumor formation when Rb expression is lost. Recent characterizations of Rb-associated proteins may provide some clues as t …
However, it is difficult to rationalize the expression of pRb in a wide range of tissues with the fact that only limited cell types a …
CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F.
van Wijnen AJ, van Gurp MF, de Ridder MC, Tufarelli C, Last TJ, Birnbaum M, Vaughan PS, Giordano A, Krek W, Neufeld EJ, Stein JL, Stein GS. van Wijnen AJ, et al. Among authors: giordano a. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11516-21. doi: 10.1073/pnas.93.21.11516. Proc Natl Acad Sci U S A. 1996. PMID: 8876167 Free PMC article.
We have previously shown that the promoter complex HiNF-D, which interacts with cell cycle control elements in multiple histone genes, contains the key cell cycle factors cyclin A, CDC2, and a retinoblastoma (pRB) protein-related protein. ...Hence, DNA replication-d …
We have previously shown that the promoter complex HiNF-D, which interacts with cell cycle control elements in multiple histone genes, conta …
2,209 results
Jump to page
Feedback