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Novel Insights into the PKCβ-dependent Regulation of the Oxidoreductase p66Shc.
Haller M, Khalid S, Kremser L, Fresser F, Furlan T, Hermann M, Guenther J, Drasche A, Leitges M, Giorgio M, Baier G, Lindner H, Troppmair J. Haller M, et al. Among authors: giorgio m. J Biol Chem. 2016 Nov 4;291(45):23557-23568. doi: 10.1074/jbc.M116.752766. Epub 2016 Sep 13. J Biol Chem. 2016. PMID: 27624939 Free PMC article.
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.
Orsini F, Migliaccio E, Moroni M, Contursi C, Raker VA, Piccini D, Martin-Padura I, Pelliccia G, Trinei M, Bono M, Puri C, Tacchetti C, Ferrini M, Mannucci R, Nicoletti I, Lanfrancone L, Giorgio M, Pelicci PG. Orsini F, et al. Among authors: giorgio m. J Biol Chem. 2004 Jun 11;279(24):25689-95. doi: 10.1074/jbc.M401844200. Epub 2004 Apr 12. J Biol Chem. 2004. PMID: 15078873 Free article.
p66Shc-generated oxidative signal promotes fat accumulation.
Berniakovich I, Trinei M, Stendardo M, Migliaccio E, Minucci S, Bernardi P, Pelicci PG, Giorgio M. Berniakovich I, et al. Among authors: giorgio m. J Biol Chem. 2008 Dec 5;283(49):34283-93. doi: 10.1074/jbc.M804362200. Epub 2008 Oct 6. J Biol Chem. 2008. PMID: 18838380 Free PMC article.
245 results