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Vitamin A improves insulin sensitivity by increasing insulin receptor phosphorylation through protein tyrosine phosphatase 1B regulation at early age in obese rats of WNIN/Ob strain.
Jeyakumar SM, Vijaya Kumar P, Giridharan NV, Vajreswari A. Jeyakumar SM, et al. Among authors: giridharan nv. Diabetes Obes Metab. 2011 Oct;13(10):955-8. doi: 10.1111/j.1463-1326.2011.01407.x. Diabetes Obes Metab. 2011. PMID: 21466649
WNIN/GR-Ob - an insulin-resistant obese rat model from inbred WNIN strain.
Harishankar N, Vajreswari A, Giridharan NV. Harishankar N, et al. Among authors: giridharan nv. Indian J Med Res. 2011 Sep;134(3):320-9. Indian J Med Res. 2011. PMID: 21985815 Free PMC article.
Vitamin A regulates obesity in WNIN/Ob obese rat; independent of stearoyl-CoA desaturase-1.
Jeyakumar SM, Vajreswari A, Giridharan NV. Jeyakumar SM, et al. Among authors: giridharan nv. Biochem Biophys Res Commun. 2008 May 30;370(2):243-7. doi: 10.1016/j.bbrc.2008.03.073. Epub 2008 Mar 24. Biochem Biophys Res Commun. 2008. PMID: 18364238
Vitamin A supplementation induces adipose tissue loss through apoptosis in lean but not in obese rats of the WNIN/Ob strain.
Jeyakumar SM, Vajreswari A, Sesikeran B, Giridharan NV. Jeyakumar SM, et al. Among authors: giridharan nv. J Mol Endocrinol. 2005 Oct;35(2):391-8. doi: 10.1677/jme.1.01838. J Mol Endocrinol. 2005. PMID: 16216918
Deriving at candidate genes of metabolic stress from pancreas of WNIN/GR-Ob mutant rats.
Singh H, Giridharan N, Bhonde R, Venkatesan V. Singh H, et al. Islets. 2013 Jul-Aug;5(4):133-8. doi: 10.4161/isl.25520. Epub 2013 Jul 1. Islets. 2013. PMID: 24131929
Obesity associated pathophysiological & histological changes in WNIN obese mutant rats.
Harishankar N, Kumar PU, Sesikeran B, Giridharan N. Harishankar N, et al. Indian J Med Res. 2011 Sep;134(3):330-40. Indian J Med Res. 2011. PMID: 21985816 Free PMC article.
Increased risk of cataract development in WNIN-obese rats due to accumulation of intralenticular sorbitol.
Reddy PY, Giridharan NV, Balakrishna N, Validandi V, Pullakhandam R, Reddy GB. Reddy PY, et al. Among authors: giridharan nv. IUBMB Life. 2013 May;65(5):472-8. doi: 10.1002/iub.1163. Epub 2013 Mar 18. IUBMB Life. 2013. PMID: 23504868 Free article.
Altered ubiquitin-proteasome system leads to neuronal cell death in a spontaneous obese rat model.
Reddy SS, Shruthi K, Reddy VS, Raghu G, Suryanarayana P, Giridharan NV, Reddy GB. Reddy SS, et al. Among authors: giridharan nv. Biochim Biophys Acta. 2014 Sep;1840(9):2924-34. doi: 10.1016/j.bbagen.2014.06.005. Epub 2014 Jun 17. Biochim Biophys Acta. 2014. PMID: 24949983
Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of WNIN/Ob, a novel rat model of premature aging.
Sinha JK, Ghosh S, Swain U, Giridharan NV, Raghunath M. Sinha JK, et al. Among authors: giridharan nv. Neuroscience. 2014 Jun 6;269:256-64. doi: 10.1016/j.neuroscience.2014.03.040. Epub 2014 Apr 5. Neuroscience. 2014. PMID: 24709042
Prenatal and perinatal zinc restriction: effects on body composition, glucose tolerance and insulin response in rat offspring.
Padmavathi IJ, Kishore YD, Venu L, Ganeshan M, Harishankar N, Giridharan NV, Raghunath M. Padmavathi IJ, et al. Among authors: giridharan nv. Exp Physiol. 2009 Jun;94(6):761-9. doi: 10.1113/expphysiol.2008.045856. Epub 2009 Feb 27. Exp Physiol. 2009. PMID: 19251982
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