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dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.
Manitt C, Eng C, Pokinko M, Ryan RT, Torres-Berrío A, Lopez JP, Yogendran SV, Daubaras MJ, Grant A, Schmidt ER, Tronche F, Krimpenfort P, Cooper HM, Pasterkamp RJ, Kolb B, Turecki G, Wong TP, Nestler EJ, Giros B, Flores C. Manitt C, et al. Among authors: giros b. Transl Psychiatry. 2013 Dec 17;3(12):e338. doi: 10.1038/tp.2013.105. Transl Psychiatry. 2013. PMID: 24346136 Free PMC article.
Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.
De Magalhaes Filho CD, Kappeler L, Dupont J, Solinc J, Villapol S, Denis C, Nosten-Bertrand M, Billard JM, Blaise A, Tronche F, Giros B, Charriaut-Marlangue C, Aïd S, Le Bouc Y, Holzenberger M. De Magalhaes Filho CD, et al. Among authors: giros b. J Cereb Blood Flow Metab. 2017 Feb;37(2):396-412. doi: 10.1177/0271678X15626718. Epub 2016 Jul 20. J Cereb Blood Flow Metab. 2017. PMID: 26762506 Free PMC article.
Antidepressive effects of targeting ELK-1 signal transduction.
Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP, Grenier J, Ibrahim EC, El Khoury MA, Tse YC, Mongredien R, Barbé A, de Macedo CEA, Jaworski W, Bochereau A, Orrico A, Isingrini E, Guinaudie C, Mikasova L, Louis F, Gautron S, Groc L, Massaad C, Yildirim F, Vialou V, Dumas S, Marti F, Mechawar N, Morice E, Wong TP, Caboche J, Turecki G, Giros B, Tzavara ET. Apazoglou K, et al. Among authors: giros b. Nat Med. 2018 May;24(5):591-597. doi: 10.1038/s41591-018-0011-0. Epub 2018 May 7. Nat Med. 2018. PMID: 29736027
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments.
Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P. Petrelli F, et al. Among authors: giros b. Mol Psychiatry. 2020 Apr;25(4):732-749. doi: 10.1038/s41380-018-0226-y. Epub 2018 Aug 20. Mol Psychiatry. 2020. PMID: 30127471 Free PMC article.
GPR56/ADGRG1 is associated with response to antidepressant treatment.
Belzeaux R, Gorgievski V, Fiori LM, Lopez JP, Grenier J, Lin R, Nagy C, Ibrahim EC, Gascon E, Courtet P, Richard-Devantoy S, Berlim M, Chachamovich E, Théroux JF, Dumas S, Giros B, Rotzinger S, Soares CN, Foster JA, Mechawar N, Tall GG, Tzavara ET, Kennedy SH, Turecki G. Belzeaux R, et al. Among authors: giros b. Nat Commun. 2020 Apr 2;11(1):1635. doi: 10.1038/s41467-020-15423-5. Nat Commun. 2020. PMID: 32242018 Free PMC article. Clinical Trial.
205 results