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Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation.
Angelova PR, Choi ML, Berezhnov AV, Horrocks MH, Hughes CD, De S, Rodrigues M, Yapom R, Little D, Dolt KS, Kunath T, Devine MJ, Gissen P, Shchepinov MS, Sylantyev S, Pavlov EV, Klenerman D, Abramov AY, Gandhi S. Angelova PR, et al. Among authors: gissen p. Cell Death Differ. 2020 Oct;27(10):2781-2796. doi: 10.1038/s41418-020-0542-z. Epub 2020 Apr 27. Cell Death Differ. 2020. PMID: 32341450 Free PMC article.
Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease.
Deas E, Cremades N, Angelova PR, Ludtmann MH, Yao Z, Chen S, Horrocks MH, Banushi B, Little D, Devine MJ, Gissen P, Klenerman D, Dobson CM, Wood NW, Gandhi S, Abramov AY. Deas E, et al. Among authors: gissen p. Antioxid Redox Signal. 2016 Mar 1;24(7):376-91. doi: 10.1089/ars.2015.6343. Epub 2016 Feb 1. Antioxid Redox Signal. 2016. PMID: 26564470 Free PMC article.
Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells.
Lorvellec M, Scottoni F, Crowley C, Fiadeiro R, Maghsoudlou P, Pellegata AF, Mazzacuva F, Gjinovci A, Lyne AM, Zulini J, Little D, Mosaku O, Kelly D, De Coppi P, Gissen P. Lorvellec M, et al. Among authors: gissen p. PLoS One. 2017 Dec 20;12(12):e0189586. doi: 10.1371/journal.pone.0189586. eCollection 2017. PLoS One. 2017. PMID: 29261712 Free PMC article.
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.
Ludtmann MHR, Angelova PR, Horrocks MH, Choi ML, Rodrigues M, Baev AY, Berezhnov AV, Yao Z, Little D, Banushi B, Al-Menhali AS, Ranasinghe RT, Whiten DR, Yapom R, Dolt KS, Devine MJ, Gissen P, Kunath T, Jaganjac M, Pavlov EV, Klenerman D, Abramov AY, Gandhi S. Ludtmann MHR, et al. Among authors: gissen p. Nat Commun. 2018 Jun 12;9(1):2293. doi: 10.1038/s41467-018-04422-2. Nat Commun. 2018. PMID: 29895861 Free PMC article.
An Optimized Method for the Proteomic Analysis of Low Volumes of Cell Culture Media and the Secretome: The Application and the Demonstration of Altered Protein Expression in iPSC-Derived Neuronal Cell Lines from Parkinson's Disease Patients.
Baud A, Little D, Wen TQ, Heywood WE, Gissen P, Mills K. Baud A, et al. Among authors: gissen p. J Proteome Res. 2019 Mar 1;18(3):1198-1207. doi: 10.1021/acs.jproteome.8b00831. Epub 2019 Jan 7. J Proteome Res. 2019. PMID: 30562036
Preparation of iPSCs for Targeted Proteomic Analysis.
Baud A, Heywood WE, Little D, Gissen P, Mills K. Baud A, et al. Among authors: gissen p. Methods Mol Biol. 2019;1994:131-139. doi: 10.1007/978-1-4939-9477-9_11. Methods Mol Biol. 2019. PMID: 31124110
191 results