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Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop.
Giannelli V, Fontana MR, Giuliani MM, Guangcai D, Rappuoli R, Pizza M. Giannelli V, et al. Among authors: giuliani mm. Infect Immun. 1997 Jan;65(1):331-4. doi: 10.1128/iai.65.1.331-334.1997. Infect Immun. 1997. PMID: 8975934 Free PMC article.
To generate nontoxic derivatives of Escherichia coli heat-labile enterotoxin (LT), site-directed mutagenesis has been used to change either the amino acid residues located in the catalytic site (M. Pizza, M. Domenighini, W. Hol, V. Giannelli, M. R. Fontana, …
To generate nontoxic derivatives of Escherichia coli heat-labile enterotoxin (LT), site-directed mutagenesis has been used to change either …
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant.
Marchetti M, Rossi M, Giannelli V, Giuliani MM, Pizza M, Censini S, Covacci A, Massari P, Pagliaccia C, Manetti R, Telford JL, Douce G, Dougan G, Rappuoli R, Ghiara P. Marchetti M, et al. Among authors: giuliani mm. Vaccine. 1998 Jan;16(1):33-7. doi: 10.1016/s0264-410x(97)00153-9. Vaccine. 1998. PMID: 9607006
Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.
Pizza M, Scarlato V, Masignani V, Giuliani MM, Aricò B, Comanducci M, Jennings GT, Baldi L, Bartolini E, Capecchi B, Galeotti CL, Luzzi E, Manetti R, Marchetti E, Mora M, Nuti S, Ratti G, Santini L, Savino S, Scarselli M, Storni E, Zuo P, Broeker M, Hundt E, Knapp B, Blair E, Mason T, Tettelin H, Hood DW, Jeffries AC, Saunders NJ, Granoff DM, Venter JC, Moxon ER, Grandi G, Rappuoli R. Pizza M, et al. Among authors: giuliani mm. Science. 2000 Mar 10;287(5459):1816-20. doi: 10.1126/science.287.5459.1816. Science. 2000. PMID: 10710308
LTK63 and LTR72, two mucosal adjuvants ready for clinical trials.
Pizza M, Giuliani MM, Fontana MR, Douce G, Dougan G, Rappuoli R. Pizza M, et al. Among authors: giuliani mm. Int J Med Microbiol. 2000 Oct;290(4-5):455-61. doi: 10.1016/S1438-4221(00)80064-8. Int J Med Microbiol. 2000. PMID: 11111926 Review. No abstract available.
NadA, a novel vaccine candidate of Neisseria meningitidis.
Comanducci M, Bambini S, Brunelli B, Adu-Bobie J, Aricò B, Capecchi B, Giuliani MM, Masignani V, Santini L, Savino S, Granoff DM, Caugant DA, Pizza M, Rappuoli R, Mora M. Comanducci M, et al. Among authors: giuliani mm. J Exp Med. 2002 Jun 3;195(11):1445-54. doi: 10.1084/jem.20020407. J Exp Med. 2002. PMID: 12045242 Free PMC article.
Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870.
Masignani V, Comanducci M, Giuliani MM, Bambini S, Adu-Bobie J, Arico B, Brunelli B, Pieri A, Santini L, Savino S, Serruto D, Litt D, Kroll S, Welsch JA, Granoff DM, Rappuoli R, Pizza M. Masignani V, et al. Among authors: giuliani mm. J Exp Med. 2003 Mar 17;197(6):789-99. doi: 10.1084/jem.20021911. J Exp Med. 2003. PMID: 12642606 Free PMC article.
846 results