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Specifically targeted gene therapy for small-cell lung cancer.
Christensen CL, Zandi R, Gjetting T, Cramer F, Poulsen HS. Christensen CL, et al. Expert Rev Anticancer Ther. 2009 Apr;9(4):437-52. doi: 10.1586/era.09.10. Expert Rev Anticancer Ther. 2009. PMID: 19374598
In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines.
Roursgaard M, Knudsen KB, Northeved H, Persson M, Christensen T, Kumar PEK, Permin A, Andresen TL, Gjetting T, Lykkesfeldt J, Vesterdal LK, Loft S, Møller P. Roursgaard M, et al. Among authors: gjetting t. Toxicol In Vitro. 2016 Oct;36:164-171. doi: 10.1016/j.tiv.2016.08.002. Epub 2016 Aug 3. Toxicol In Vitro. 2016. PMID: 27497994
A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue.
Gjetting T, Andresen TL, Christensen CL, Cramer F, Poulsen TT, Poulsen HS. Gjetting T, et al. Results Pharma Sci. 2011 Sep 3;1(1):49-56. doi: 10.1016/j.rinphs.2011.08.001. eCollection 2011 May. Results Pharma Sci. 2011. PMID: 25755981 Free PMC article.
In vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection.
Gjetting T, Arildsen NS, Christensen CL, Poulsen TT, Roth JA, Handlos VN, Poulsen HS. Gjetting T, et al. Int J Nanomedicine. 2010 Aug 9;5:371-83. doi: 10.2147/ijn.s10462. Int J Nanomedicine. 2010. PMID: 20957159 Free PMC article.
Targeted cytosine deaminase-uracil phosphoribosyl transferase suicide gene therapy induces small cell lung cancer-specific cytotoxicity and tumor growth delay.
Christensen CL, Gjetting T, Poulsen TT, Cramer F, Roth JA, Poulsen HS. Christensen CL, et al. Among authors: gjetting t. Clin Cancer Res. 2010 Apr 15;16(8):2308-19. doi: 10.1158/1078-0432.CCR-09-3057. Epub 2010 Apr 6. Clin Cancer Res. 2010. PMID: 20371678 Free PMC article.
In vivo toxicity of cationic micelles and liposomes.
Knudsen KB, Northeved H, Kumar PE, Permin A, Gjetting T, Andresen TL, Larsen S, Wegener KM, Lykkesfeldt J, Jantzen K, Loft S, Møller P, Roursgaard M. Knudsen KB, et al. Among authors: gjetting t. Nanomedicine. 2015 Feb;11(2):467-77. doi: 10.1016/j.nano.2014.08.004. Epub 2014 Aug 25. Nanomedicine. 2015. PMID: 25168934 Free article.
Investigation of enzyme-sensitive lipid nanoparticles for delivery of siRNA to blood-brain barrier and glioma cells.
Bruun J, Larsen TB, Jølck RI, Eliasen R, Holm R, Gjetting T, Andresen TL. Bruun J, et al. Among authors: gjetting t. Int J Nanomedicine. 2015 Sep 24;10:5995-6008. doi: 10.2147/IJN.S87334. eCollection 2015. Int J Nanomedicine. 2015. PMID: 26451106 Free PMC article.
Effective nanoparticle-based gene delivery by a protease triggered charge switch.
Gjetting T, Jølck RI, Andresen TL. Gjetting T, et al. Adv Healthc Mater. 2014 Jul;3(7):1107-18. doi: 10.1002/adhm.201300503. Epub 2014 Mar 20. Adv Healthc Mater. 2014. PMID: 24652709
Side chain hydrophobicity modulates therapeutic activity and membrane selectivity of antimicrobial peptide mastoparan-X.
Henriksen JR, Etzerodt T, Gjetting T, Andresen TL. Henriksen JR, et al. Among authors: gjetting t. PLoS One. 2014 Mar 12;9(3):e91007. doi: 10.1371/journal.pone.0091007. eCollection 2014. PLoS One. 2014. PMID: 24621994 Free PMC article.
A modified protocol for efficient DNA encapsulation into pegylated immunoliposomes (PILs).
Skjørringe T, Gjetting T, Jensen TG. Skjørringe T, et al. J Control Release. 2009 Oct 15;139(2):140-5. doi: 10.1016/j.jconrel.2009.06.009. Epub 2009 Jun 21. J Control Release. 2009. PMID: 19545595
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