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Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires.
Gleimer M, Wahl AR, Hickman HD, Abi-Rached L, Norman PJ, Guethlein LA, Hammond JA, Draghi M, Adams EJ, Juo S, Jalili R, Gharizadeh B, Ronaghi M, Garcia KC, Hildebrand WH, Parham P. Gleimer M, et al. J Immunol. 2011 Feb 1;186(3):1575-88. doi: 10.4049/jimmunol.1002990. Epub 2011 Jan 5. J Immunol. 2011. PMID: 21209280 Free PMC article.
Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans.
Norman PJ, Abi-Rached L, Gendzekhadze K, Korbel D, Gleimer M, Rowley D, Bruno D, Carrington CV, Chandanayingyong D, Chang YH, Crespí C, Saruhan-Direskeneli G, Fraser PA, Hameed K, Kamkamidze G, Koram KA, Layrisse Z, Matamoros N, Milà J, Park MH, Pitchappan RM, Ramdath DD, Shiau MY, Stephens HA, Struik S, Verity DH, Vaughan RW, Tyan D, Davis RW, Riley EM, Ronaghi M, Parham P. Norman PJ, et al. Among authors: gleimer m. Nat Genet. 2007 Sep;39(9):1092-9. doi: 10.1038/ng2111. Epub 2007 Aug 12. Nat Genet. 2007. PMID: 17694054
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