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The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.
Gustafsen C, Kjolby M, Nyegaard M, Mattheisen M, Lundhede J, Buttenschøn H, Mors O, Bentzon JF, Madsen P, Nykjaer A, Glerup S. Gustafsen C, et al. Among authors: glerup s. Cell Metab. 2014 Feb 4;19(2):310-8. doi: 10.1016/j.cmet.2013.12.006. Cell Metab. 2014. PMID: 24506872 Free article.
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
Klinger SC, Glerup S, Raarup MK, Mari MC, Nyegaard M, Koster G, Prabakaran T, Nilsson SK, Kjaergaard MM, Bakke O, Nykjær A, Olivecrona G, Petersen CM, Nielsen MS. Klinger SC, et al. Among authors: glerup s. J Cell Sci. 2011 Apr 1;124(Pt 7):1095-105. doi: 10.1242/jcs.072538. Epub 2011 Mar 8. J Cell Sci. 2011. PMID: 21385844 Free article.
Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosis.
Skeldal S, Sykes AM, Glerup S, Matusica D, Palstra N, Autio H, Boskovic Z, Madsen P, Castrén E, Nykjaer A, Coulson EJ. Skeldal S, et al. Among authors: glerup s. J Biol Chem. 2012 Dec 21;287(52):43798-809. doi: 10.1074/jbc.M112.374710. Epub 2012 Oct 26. J Biol Chem. 2012. PMID: 23105113 Free PMC article.
Sortilins in neurotrophic factor signaling.
Glerup S, Nykjaer A, Vaegter CB. Glerup S, et al. Handb Exp Pharmacol. 2014;220:165-89. doi: 10.1007/978-3-642-45106-5_7. Handb Exp Pharmacol. 2014. PMID: 24668473 Review.
52 results