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Behavioral effects of food-derived opioid-like peptides in rodents: Implications for schizophrenia?
Lister J, Fletcher PJ, Nobrega JN, Remington G. Lister J, et al. Pharmacol Biochem Behav. 2015 Jul;134:70-8. doi: 10.1016/j.pbb.2015.01.020. Epub 2015 Feb 7. Pharmacol Biochem Behav. 2015. PMID: 25661529 Review.
Surprisingly, only a single study evaluating a gluten-derived peptide (gliadorphin-7; GD-7, n=1) was identified and included in this review. In conclusion, food-derived peptides can affect rodent behavior, but more studies of GDs using diverse behavioral batteries are warr …
Surprisingly, only a single study evaluating a gluten-derived peptide (gliadorphin-7; GD-7, n=1) was identified and included in this …
Findings in normal rats following administration of gliadorphin-7 (GD-7).
Sun Z, Cade R. Sun Z, et al. Peptides. 2003 Feb;24(2):321-3. doi: 10.1016/s0196-9781(03)00043-3. Peptides. 2003. PMID: 12668219
This paper discusses the effects of gliadorphin-7 (GD-7) infusion in rats and contrasts them with those of beta-casomorphin-7 (betaC-7). ...
This paper discusses the effects of gliadorphin-7 (GD-7) infusion in rats and contrasts them with those of beta-casomorphin-7 (betaC- …
Degradation of food-derived opioid peptides by bifidobacteria.
Sakurai T, Yamada A, Hashikura N, Odamaki T, Xiao JZ. Sakurai T, et al. Benef Microbes. 2018 Jun 15;9(4):675-682. doi: 10.3920/BM2017.0165. Epub 2018 Apr 10. Benef Microbes. 2018. PMID: 29633643
In addition, some B. longum subsp. infantis and B. bifidum strains showed degradative activity in food-derived opioid peptides such as human and bovine milk-derived casomorphin-7 and wheat gluten-derived gliadorphin-7. A further screening of B. bifidum strains revealed som …
In addition, some B. longum subsp. infantis and B. bifidum strains showed degradative activity in food-derived opioid peptides such as human …
Lower Diversity of Amylase-Trypsin Inhibitors and Ex Vivo-Released Opioid-Containing Peptides in Ancestral Compared to Modern Wheat Varieties Assessed by Proteomics and Peptidomics.
Asledottir T, Mamone G, Picariello G, Vegarud GE, Røseth A, Ferranti P, Devold TG. Asledottir T, et al. J Agric Food Chem. 2025 Jan 29;73(4):2373-2380. doi: 10.1021/acs.jafc.4c05959. Epub 2025 Jan 15. J Agric Food Chem. 2025. PMID: 39813239 Free PMC article.
Nevertheless, digestion of Mirakel and Bastian by human gastrointestinal juices released the highest number of opioid-containing peptides, representing both gluten exorphins and gliadorphin. In conclusion, emmer had the lowest levels of ATIs, while einkorn and spelt releas …
Nevertheless, digestion of Mirakel and Bastian by human gastrointestinal juices released the highest number of opioid-containing peptides, r …
Autism and Schizophrenia: Intestinal Disorders.
Cade R, Privette M, Fregly M, Rowland N, Sun Z, Zele V, Wagemaker H, Edelstein C. Cade R, et al. Nutr Neurosci. 2000;3(1):57-72. doi: 10.1080/1028415X.2000.11747303. Nutr Neurosci. 2000. PMID: 27416160