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Targeting the NLRP3 inflammasome in inflammatory diseases.
Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E. Mangan MSJ, et al. Among authors: glick gd. Nat Rev Drug Discov. 2018 Aug;17(8):588-606. doi: 10.1038/nrd.2018.97. Epub 2018 Jul 20. Nat Rev Drug Discov. 2018. PMID: 30026524 Review.
Targeting the NLRP3 inflammasome in inflammatory diseases.
Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E. Mangan MSJ, et al. Among authors: glick gd. Nat Rev Drug Discov. 2018 Sep;17(9):688. doi: 10.1038/nrd.2018.149. Epub 2018 Aug 17. Nat Rev Drug Discov. 2018. PMID: 30116046
Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis.
Franchi L, Monteleone I, Hao LY, Spahr MA, Zhao W, Liu X, Demock K, Kulkarni A, Lesch CA, Sanchez B, Carter L, Marafini I, Hu X, Mashadova O, Yuan M, Asara JM, Singh H, Lyssiotis CA, Monteleone G, Opipari AW, Glick GD. Franchi L, et al. Among authors: glick gd. J Immunol. 2017 Apr 1;198(7):2735-2746. doi: 10.4049/jimmunol.1600810. Epub 2017 Feb 27. J Immunol. 2017. PMID: 28242647 Free PMC article.
Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity.
Hu X, Liu X, Moisan J, Wang Y, Lesch CA, Spooner C, Morgan RW, Zawidzka EM, Mertz D, Bousley D, Majchrzak K, Kryczek I, Taylor C, Van Huis C, Skalitzky D, Hurd A, Aicher TD, Toogood PL, Glick GD, Paulos CM, Zou W, Carter LL. Hu X, et al. Among authors: glick gd. Oncoimmunology. 2016 Nov 4;5(12):e1254854. doi: 10.1080/2162402X.2016.1254854. eCollection 2016. Oncoimmunology. 2016. PMID: 28123897 Free PMC article.
RORγt inhibitors suppress T(H)17 responses in inflammatory arthritis and inflammatory bowel disease.
de Wit J, Al-Mossawi MH, Hühn MH, Arancibia-Cárcamo CV, Doig K, Kendrick B, Gundle R, Taylor P, Mcclanahan T, Murphy E, Zhang H, Barr K, Miller JR, Hu X, Aicher TD, Morgan RW, Glick GD, Zaller D, Correll C, Powrie F, Bowness P. de Wit J, et al. Among authors: glick gd. J Allergy Clin Immunol. 2016 Mar;137(3):960-3. doi: 10.1016/j.jaci.2015.09.048. Epub 2015 Nov 21. J Allergy Clin Immunol. 2016. PMID: 26611672 No abstract available.
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