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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
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2010 2
2011 1
2012 2
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2015 9
2016 11
2017 17
2018 24
2019 27
2020 40
2021 65
2022 56
2023 92
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487 results

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Page 1
Primary stroke prevention worldwide: translating evidence into action.
Owolabi MO, Thrift AG, Mahal A, Ishida M, Martins S, Johnson WD, Pandian J, Abd-Allah F, Yaria J, Phan HT, Roth G, Gall SL, Beare R, Phan TG, Mikulik R, Akinyemi RO, Norrving B, Brainin M, Feigin VL; Stroke Experts Collaboration Group. Owolabi MO, et al. Lancet Public Health. 2022 Jan;7(1):e74-e85. doi: 10.1016/S2468-2667(21)00230-9. Epub 2021 Oct 29. Lancet Public Health. 2022. PMID: 34756176 Free PMC article. Review.
We also offer a set of pragmatic solutions for implementation of primary stroke prevention, with an emphasis on the role of governments and population-wide strategies, including task-shifting and sharing and health system re-engineering. Implementation of primary st …
We also offer a set of pragmatic solutions for implementation of primary stroke prevention, with an emphasis on the role of governmen …
Pharmacogenomics: current status and future perspectives.
Pirmohamed M. Pirmohamed M. Nat Rev Genet. 2023 Jun;24(6):350-362. doi: 10.1038/s41576-022-00572-8. Epub 2023 Jan 27. Nat Rev Genet. 2023. PMID: 36707729 Review.
Inter-individual variability in drug response, be it efficacy or safety, is common and likely to become an increasing problem globally given the growing elderly population requiring treatment. Reasons for this inter-individual variability include genomic factors, an …
Inter-individual variability in drug response, be it efficacy or safety, is common and likely to become an increasing problem globally …
Tuberculous meningitis: progress and remaining questions.
Huynh J, Donovan J, Phu NH, Nghia HDT, Thuong NTT, Thwaites GE. Huynh J, et al. Lancet Neurol. 2022 May;21(5):450-464. doi: 10.1016/S1474-4422(21)00435-X. Lancet Neurol. 2022. PMID: 35429482 Review.
Large phase 3 clinical trials are underway worldwide to address these and other questions concerning the optimal management of tuberculous meningitis; these studies also form a platform for studying pathogenesis and identifying novel diagnostic and treatment strategies, by allowi …
Large phase 3 clinical trials are underway worldwide to address these and other questions concerning the optimal management of tuberculous m …
Introduction to pharmacogenetics.
McDermott JH, Newman W. McDermott JH, et al. Drug Ther Bull. 2023 Nov;61(11):168-172. doi: 10.1136/dtb.2023.000009. Epub 2023 Oct 3. Drug Ther Bull. 2023. PMID: 37788890 Review.
This article provides an introduction to the field of pharmacogenetics, including its nomenclature, the existing evidence base and the current state of implementation globally. We discuss the challenges in translating pharmacogenetic research into clinical practice …
This article provides an introduction to the field of pharmacogenetics, including its nomenclature, the existing evidence base and the curre …
Delivering precision oncology to patients with cancer.
Mateo J, Steuten L, Aftimos P, André F, Davies M, Garralda E, Geissler J, Husereau D, Martinez-Lopez I, Normanno N, Reis-Filho JS, Stefani S, Thomas DM, Westphalen CB, Voest E. Mateo J, et al. Nat Med. 2022 Apr;28(4):658-665. doi: 10.1038/s41591-022-01717-2. Epub 2022 Apr 19. Nat Med. 2022. PMID: 35440717 Review.
With the increasing use of genomic profiling for diagnosis and therapy guidance in many tumor types, precision oncology is rapidly reshaping cancer care. ...A multi-stakeholder approach to evidence generation, value assessment, and healthcare delivery is necessary to trans …
With the increasing use of genomic profiling for diagnosis and therapy guidance in many tumor types, precision oncology is rapidly re …
Sequencing of Circulating Cell-free DNA during Pregnancy.
Bianchi DW, Chiu RWK. Bianchi DW, et al. N Engl J Med. 2018 Aug 2;379(5):464-473. doi: 10.1056/NEJMra1705345. N Engl J Med. 2018. PMID: 30067923 Free PMC article. Review.
Sequence analysis of cell-free DNA (cfDNA) fragments that circulate in the blood of pregnant women, along with the translation of this method into screening for fetal chromosome abnormalities, is a success story of modern genomic medicine. In less than a decade, pre …
Sequence analysis of cell-free DNA (cfDNA) fragments that circulate in the blood of pregnant women, along with the translation of this metho …
World Heart Federation Cholesterol Roadmap 2022.
Ray KK, Ference BA, Séverin T, Blom D, Nicholls SJ, Shiba MH, Almahmeed W, Alonso R, Daccord M, Ezhov M, Olmo RF, Jankowski P, Lanas F, Mehta R, Puri R, Wong ND, Wood D, Zhao D, Gidding SS, Virani SS, Lloyd-Jones D, Pinto F, Perel P, Santos RD. Ray KK, et al. Glob Heart. 2022 Oct 14;17(1):75. doi: 10.5334/gh.1154. eCollection 2022. Glob Heart. 2022. PMID: 36382159 Free PMC article. Review.
BACKGROUND: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue to be major causes of premature death, disability and healthcare expenditure globally. Preventing the accumulation of cholesterol-co …
BACKGROUND: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue …
Hazardous drinking and alcohol use disorders.
MacKillop J, Agabio R, Feldstein Ewing SW, Heilig M, Kelly JF, Leggio L, Lingford-Hughes A, Palmer AA, Parry CD, Ray L, Rehm J. MacKillop J, et al. Nat Rev Dis Primers. 2022 Dec 22;8(1):80. doi: 10.1038/s41572-022-00406-1. Nat Rev Dis Primers. 2022. PMID: 36550121 Free PMC article. Review.
Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous drinking, defined by quantity and frequency of consumption, is associated with acute and chronic morbidity. ...Priorities for the field include translating advances in basic biobehavioural re …
Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous drinking, defined by quantity and frequency of cons …
Global approaches to genomic medicine implementation.
Belcher A, Ginsburg GS, Ward R. Belcher A, et al. Sci Transl Med. 2020 Sep 30;12(563):eaax0911. doi: 10.1126/scitranslmed.aax0911. Sci Transl Med. 2020. PMID: 32998968
A snapshot of large-scale genomic medicine implementation initiatives worldwide illustrates similarities in policy considerations....
A snapshot of large-scale genomic medicine implementation initiatives worldwide illustrates similarities in policy cons …
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.
Wirbel J, Pyl PT, Kartal E, Zych K, Kashani A, Milanese A, Fleck JS, Voigt AY, Palleja A, Ponnudurai R, Sunagawa S, Coelho LP, Schrotz-King P, Vogtmann E, Habermann N, Niméus E, Thomas AM, Manghi P, Gandini S, Serrano D, Mizutani S, Shiroma H, Shiba S, Shibata T, Yachida S, Yamada T, Waldron L, Naccarati A, Segata N, Sinha R, Ulrich CM, Brenner H, Arumugam M, Bork P, Zeller G. Wirbel J, et al. Nat Med. 2019 Apr;25(4):679-689. doi: 10.1038/s41591-019-0406-6. Epub 2019 Apr 1. Nat Med. 2019. PMID: 30936547 Free PMC article.
Through extensive validations, this meta-analysis firmly establishes globally generalizable, predictive taxonomic and functional microbiome CRC signatures as a basis for future diagnostics....
Through extensive validations, this meta-analysis firmly establishes globally generalizable, predictive taxonomic and functional micr …
487 results