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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 2
1948 3
1949 3
1950 12
1951 17
1952 22
1953 35
1954 30
1955 157
1956 419
1957 583
1958 634
1959 724
1960 699
1961 582
1962 722
1963 1292
1964 1743
1965 1216
1966 1349
1967 1730
1968 1863
1969 2088
1970 1948
1971 2204
1972 2212
1973 2386
1974 2563
1975 2329
1976 2186
1977 2173
1978 2292
1979 2284
1980 2280
1981 2301
1982 2652
1983 2930
1984 3210
1985 3248
1986 3151
1987 3233
1988 3234
1989 3477
1990 3641
1991 3718
1992 3965
1993 4066
1994 4146
1995 4166
1996 4241
1997 4305
1998 4609
1999 4600
2000 4858
2001 4731
2002 4981
2003 5310
2004 5386
2005 5872
2006 6481
2007 6456
2008 6521
2009 6728
2010 6888
2011 7141
2012 7533
2013 7513
2014 7621
2015 7748
2016 7491
2017 7526
2018 7936
2019 7873
2020 8353
2021 8140
2022 7196
2023 6669
2024 6805
2025 7145
2026 3604

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269,256 results

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Page 1
Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids.
Czock D, Keller F, Rasche FM, Häussler U. Czock D, et al. Clin Pharmacokinet. 2005;44(1):61-98. doi: 10.2165/00003088-200544010-00003. Clin Pharmacokinet. 2005. PMID: 15634032 Review.
Nongenomic mechanisms might play an additional role in glucocorticoid pulse therapy. Clinical efficacy depends on glucocorticoid pharmacokinetics and pharmacodynamics. ...These simulations suggest that the clinical efficacy of low-dose glucocorticoid regimens …
Nongenomic mechanisms might play an additional role in glucocorticoid pulse therapy. Clinical efficacy depends on glucocorticoid …
Therapeutic Mechanisms of Glucocorticoids.
Vandewalle J, Luypaert A, De Bosscher K, Libert C. Vandewalle J, et al. Trends Endocrinol Metab. 2018 Jan;29(1):42-54. doi: 10.1016/j.tem.2017.10.010. Epub 2017 Nov 20. Trends Endocrinol Metab. 2018. PMID: 29162310 Review.
Glucocorticoids (GCs) have been used clinically for decades as potent anti-inflammatory and immunosuppressive agents. ...The goal is to generate new glucocorticoid receptor (GR) ligands that can dissociate anti-inflammatory from metabolic side effects and/or overcom …
Glucocorticoids (GCs) have been used clinically for decades as potent anti-inflammatory and immunosuppressive agents. ...The goal is …
Anti-inflammatory actions of glucocorticoids: molecular mechanisms.
Barnes PJ. Barnes PJ. Clin Sci (Lond). 1998 Jun;94(6):557-72. doi: 10.1042/cs0940557. Clin Sci (Lond). 1998. PMID: 9854452 Review.
Glucocorticoids bind to glucocorticoid receptors in the cytoplasm which then dimerize and translocate to the nucleus, where they bind to glucocorticoid response elements (GRE) on glucocorticoid-responsive genes, resulting in increased transcription. .. …
Glucocorticoids bind to glucocorticoid receptors in the cytoplasm which then dimerize and translocate to the nucleus, where th …
Glucocorticoids.
Spies CM, Strehl C, van der Goes MC, Bijlsma JW, Buttgereit F. Spies CM, et al. Best Pract Res Clin Rheumatol. 2011 Dec;25(6):891-900. doi: 10.1016/j.berh.2011.11.002. Best Pract Res Clin Rheumatol. 2011. PMID: 22265268 Review.
In this review, we describe new insights into the mechanisms of anti-inflammatory glucocorticoid actions and provide an update on recent approaches to improve the risk/benefit ratio of glucocorticoid therapy. Improved knowledge of the immunomodulatory role of endoge …
In this review, we describe new insights into the mechanisms of anti-inflammatory glucocorticoid actions and provide an update on rec …
Glucocorticoids in Myositis: Initiation, Tapering, and Discontinuation.
Saygin D, Oddis CV. Saygin D, et al. Curr Rheumatol Rep. 2022 Mar;24(3):47-53. doi: 10.1007/s11926-022-01060-y. Epub 2022 Mar 11. Curr Rheumatol Rep. 2022. PMID: 35275363 Review.
PURPOSE OF THE REVIEW: We discuss the evidence behind the use of glucocorticoids in myositis including a discussion of mechanism of action, dosing, tapering, and duration of therapy as well as glucocorticoid-related adverse events that are particularly important in …
PURPOSE OF THE REVIEW: We discuss the evidence behind the use of glucocorticoids in myositis including a discussion of mechanism of a …
Glucocorticoids Influencing Wnt/beta-Catenin Pathway; Multiple Sites, Heterogeneous Effects.
Meszaros K, Patocs A. Meszaros K, et al. Molecules. 2020 Mar 25;25(7):1489. doi: 10.3390/molecules25071489. Molecules. 2020. PMID: 32218328 Free PMC article. Review.
Glucocorticoid hormones are vital; their accurate operation is a necessity at all ages and in all life situations. ...As the operation of these hormones affects many organs, the excess of glucocorticoids is actually detrimental to the whole human body. The endogenou …
Glucocorticoid hormones are vital; their accurate operation is a necessity at all ages and in all life situations. ...As the operatio …
Glucocorticoids: Fuelling the Fire of Atherosclerosis or Therapeutic Extinguishers?
MacLeod C, Hadoke PWF, Nixon M. MacLeod C, et al. Int J Mol Sci. 2021 Jul 16;22(14):7622. doi: 10.3390/ijms22147622. Int J Mol Sci. 2021. PMID: 34299240 Free PMC article. Review.
Atherosclerosis is the major cause of CVD, leading to complications including coronary artery disease, myocardial infarction and heart failure. While the associations between glucocorticoid excess and increased prevalence of these complications are well established, the me …
Atherosclerosis is the major cause of CVD, leading to complications including coronary artery disease, myocardial infarction and heart failu …
Glucocorticoids and chronic inflammation.
Straub RH, Cutolo M. Straub RH, et al. Rheumatology (Oxford). 2016 Dec;55(suppl 2):ii6-ii14. doi: 10.1093/rheumatology/kew348. Rheumatology (Oxford). 2016. PMID: 27856655 Review.
Glucocorticoids are steroid hormones that once bound to their receptor interact with the DNA binding domain. ...We performed a literature survey using the key words glucocorticoids, inflammation, autoimmune disease, rheumatology and adrenal glands in order to define …
Glucocorticoids are steroid hormones that once bound to their receptor interact with the DNA binding domain. ...We performed a litera …
Glucocorticoids and cardiovascular disease.
Walker BR. Walker BR. Eur J Endocrinol. 2007 Nov;157(5):545-59. doi: 10.1530/EJE-07-0455. Eur J Endocrinol. 2007. PMID: 17984234 Review.
Furthermore, glucocorticoids have direct effects on the heart and blood vessels, mediated by both glucocorticoid and mineralocorticoid receptors and modified by local metabolism of glucocorticoids by the 11beta-hydroxysteroid dehydrogenase enzymes. ...This ar …
Furthermore, glucocorticoids have direct effects on the heart and blood vessels, mediated by both glucocorticoid and mineraloc …
269,256 results
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