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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1949 3
1950 4
1951 4
1952 5
1953 11
1954 7
1955 13
1956 12
1957 26
1958 21
1959 39
1960 48
1961 61
1962 91
1963 124
1964 157
1965 182
1966 188
1967 241
1968 232
1969 267
1970 247
1971 257
1972 254
1973 285
1974 280
1975 436
1976 405
1977 399
1978 379
1979 361
1980 378
1981 413
1982 414
1983 475
1984 463
1985 453
1986 448
1987 449
1988 456
1989 439
1990 457
1991 444
1992 375
1993 376
1994 362
1995 411
1996 384
1997 318
1998 351
1999 337
2000 391
2001 359
2002 405
2003 414
2004 390
2005 428
2006 441
2007 407
2008 388
2009 396
2010 386
2011 417
2012 448
2013 515
2014 502
2015 504
2016 470
2017 473
2018 471
2019 501
2020 587
2021 513
2022 529
2023 517
2024 146

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23,040 results

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Page 1
Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance.
Leng L, Yuan Z, Pan R, Su X, Wang H, Xue J, Zhuang K, Gao J, Chen Z, Lin H, Xie W, Li H, Chen Z, Ren K, Zhang X, Wang W, Jin ZB, Wu S, Wang X, Yuan Z, Xu H, Chow HM, Zhang J. Leng L, et al. Nat Metab. 2022 Oct;4(10):1287-1305. doi: 10.1038/s42255-022-00643-4. Epub 2022 Oct 6. Nat Metab. 2022. PMID: 36203054
Notably, the ATP level is dramatically increased in HK2-deficient or inactive microglia, which can be attributed to a marked upregulation in lipoprotein lipase (LPL) expression and subsequent increase in lipid metabolism. We further show that two downstream metabolites of HK2, …
Notably, the ATP level is dramatically increased in HK2-deficient or inactive microglia, which can be attributed to a marked upregulation in …
Multiple glucose 6-phosphate pools or channelling of flux in diverse pathways?
Agius L, Centelles J, Cascante M. Agius L, et al. Biochem Soc Trans. 2002 Apr;30(2):38-43. Biochem Soc Trans. 2002. PMID: 12023820 Review.
Glucose 6-phosphate is an intermediate of pathways of glucose utilization and production as well as a regulator of enzyme activity and gene expression. Studies on the latter functions are in part based on measurement of the glucose 6-phosphat
Glucose 6-phosphate is an intermediate of pathways of glucose utilization and production as well as a regulator of enzy
Demonstration of glucose-6-phosphate hydrogen 5 enrichment from deuterated water by transaldolase-mediated exchange alone.
Coelho M, Valente-Silva P, Tylki-Szymanska A, Henriques T, Barosa C, Carvalho F, Jones JG. Coelho M, et al. Magn Reson Med. 2016 Apr;75(4):1781-6. doi: 10.1002/mrm.25749. Epub 2015 May 20. Magn Reson Med. 2016. PMID: 25995077 Free article.
Exchanges of hexose and triose phosphates mediated by transaldolase have been postulated to enrich H5 independently of gluconeogenesis, but to date this mechanism has not been proven. We determined the enrichment of glucose-6-phosphate (G6P), the immediate pr …
Exchanges of hexose and triose phosphates mediated by transaldolase have been postulated to enrich H5 independently of gluconeogenesis, but …
Insights into Glucose-6-phosphate Allosteric Activation of beta-Glucosidase A.
A Gomes A, da Silva GF, Lakkaraju SK, Guimarães BG, MacKerell AD Jr, Magalhães MLB. A Gomes A, et al. J Chem Inf Model. 2021 Apr 26;61(4):1931-1941. doi: 10.1021/acs.jcim.0c01450. Epub 2021 Apr 5. J Chem Inf Model. 2021. PMID: 33819021 Free PMC article.
However, the success of second-generation biorefineries relies on energetically efficient processes and effective enzyme cocktails to convert cellulose into fermentable sugars. beta-glucosidases catalyze the last step on the enzymatic hydrolysis of cellulose; however, they are of …
However, the success of second-generation biorefineries relies on energetically efficient processes and effective enzyme cocktails to conver …
Glucose-6-Phosphate Acts as an Extracellular Signal of SagS To Modulate Pseudomonas aeruginosa c-di-GMP Levels, Attachment, and Biofilm Formation.
Park S, Dingemans J, Gowett M, Sauer K. Park S, et al. mSphere. 2021 Feb 10;6(1):e01231-20. doi: 10.1128/mSphere.01231-20. mSphere. 2021. PMID: 33568456 Free PMC article.
Using a modified Biolog phenotype assay to screen for compounds that modulate attachment in a SagS-dependent manner, we identified glucose-6-phosphate to enhance attachment in a manner dependent on the glucose-6-phosphate concentration an …
Using a modified Biolog phenotype assay to screen for compounds that modulate attachment in a SagS-dependent manner, we identified glucos
The glucose-6-phosphate transport is not mediated by a glucose-6-phosphate/phosphate exchange in liver microsomes.
Marcolongo P, Fulceri R, Giunti R, Margittai E, Banhegyi G, Benedetti A. Marcolongo P, et al. FEBS Lett. 2012 Sep 21;586(19):3354-9. doi: 10.1016/j.febslet.2012.07.018. Epub 2012 Jul 20. FEBS Lett. 2012. PMID: 22819816 Free article.
A phosphate-linked antiporter activity of the glucose-6-phosphate transporter (G6PT) has been recently described in liposomes including the reconstituded transporter protein. We directly investigated the mechanism of glucose-6-phosphate ( …
A phosphate-linked antiporter activity of the glucose-6-phosphate transporter (G6PT) has been recently described in lip …
Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP).
Li MV, Chen W, Harmancey RN, Nuotio-Antar AM, Imamura M, Saha P, Taegtmeyer H, Chan L. Li MV, et al. Biochem Biophys Res Commun. 2010 May 7;395(3):395-400. doi: 10.1016/j.bbrc.2010.04.028. Epub 2010 Apr 9. Biochem Biophys Res Commun. 2010. PMID: 20382127 Free PMC article.
We have previously reported that high glucose can activate the transcriptional activity of ChREBP independent of the protein phosphatase 2A (PP2A)-mediated increase in nuclear entry and DNA binding. Here, we found that formation of glucose-6-phosphate (G-6-P) …
We have previously reported that high glucose can activate the transcriptional activity of ChREBP independent of the protein phosphatase 2A …
Sporophytic control of anther development and male fertility by glucose-6-phosphate/phosphate translocator 1 (OsGPT1) in rice.
Qu A, Xu Y, Yu X, Si Q, Xu X, Liu C, Yang L, Zheng Y, Zhang M, Zhang S, Xu J. Qu A, et al. J Genet Genomics. 2021 Aug 20;48(8):695-705. doi: 10.1016/j.jgg.2021.04.013. Epub 2021 Jun 7. J Genet Genomics. 2021. PMID: 34315684 Free article.
Coordination between the sporophytic tissue and the gametic pollen within anthers is tightly controlled to achieve the optimal pollen fitness. Glucose-6-phosphate/phosphate translocator (GPT) transports glucose-6-phosphate, a key precurso …
Coordination between the sporophytic tissue and the gametic pollen within anthers is tightly controlled to achieve the optimal pollen fitnes …
23,040 results
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