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Year Number of Results
1981 1
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1992 2
1993 2
1994 1
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2004 2
2005 1
2006 1
2012 1
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2017 2
2018 2
2020 1
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25 results

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Page 1
Folding Defects Leading to Primary Hyperoxaluria.
Oppici E, Dindo M, Conter C, Borri Voltattorni C, Cellini B. Oppici E, et al. Handb Exp Pharmacol. 2018;245:313-343. doi: 10.1007/164_2017_59. Handb Exp Pharmacol. 2018. PMID: 29071511 Review.
The most common and severe form, primary hyperoxaluria Type I, is due to the deficit of liver peroxisomal alanine/glyoxylate aminotransferase (AGT). Various studies performed in the last decade clearly evidence that many pathogenic missense mutations prevent the AGT correc …
The most common and severe form, primary hyperoxaluria Type I, is due to the deficit of liver peroxisomal alanine/glyoxylate aminotra …
AGXT2: a promiscuous aminotransferase.
Rodionov RN, Jarzebska N, Weiss N, Lentz SR. Rodionov RN, et al. Trends Pharmacol Sci. 2014 Nov;35(11):575-82. doi: 10.1016/j.tips.2014.09.005. Epub 2014 Oct 13. Trends Pharmacol Sci. 2014. PMID: 25294000 Free PMC article. Review.
Alanine-glyoxylate aminotransferase 2 (AGXT2) is a multifunctional mitochondrial aminotransferase that was first identified in 1978. The physiological importance of AGXT2 was largely overlooked for three decades because AGXT2 is less active in glyoxylate metabolism
Alanine-glyoxylate aminotransferase 2 (AGXT2) is a multifunctional mitochondrial aminotransferase that was first identified in
Is type 2 diabetes due to a deficiency of FAD-linked glycerophosphate dehydrogenase in pancreatic islets?
Malaisse WJ. Malaisse WJ. Acta Diabetol. 1993;30(1):1-5. doi: 10.1007/BF00572865. Acta Diabetol. 1993. PMID: 8329724 Review.
In the T-lymphocytes of type 2 diabetics the m-GDH deficiency occasionally coincided with an abnormally high ratio between glutamate-pyruvate and glutamate-oxaloacetate transaminase activities, as also observed in islets from streptozotoc …
In the T-lymphocytes of type 2 diabetics the m-GDH deficiency occasionally coincided with an abnormally high ratio between …
AGXT2: An unnegligible aminotransferase in cardiovascular and urinary systems.
Hu XL, Li MP, Song PY, Tang J, Chen XP. Hu XL, et al. J Mol Cell Cardiol. 2017 Dec;113:33-38. doi: 10.1016/j.yjmcc.2017.09.010. Epub 2017 Sep 29. J Mol Cell Cardiol. 2017. PMID: 28970090 Review.
Also, the plasma levels of ADMA and SDMA were reported to be significantly associated with renal function. Alanine-glyoxylate aminotransferase 2 (AGXT2) is reported to be involved in ADMA and SDMA metabolism, thus deficiency in the expression or activity of A …
Also, the plasma levels of ADMA and SDMA were reported to be significantly associated with renal function. Alanine-glyoxylate aminotr …
Metreleptin Treatment in Patients with Non-HIV Associated Lipodystrophy.
Akinci G, Akinci B. Akinci G, et al. Recent Pat Endocr Metab Immune Drug Discov. 2015;9(2):74-8. doi: 10.2174/1574892811666151111142554. Recent Pat Endocr Metab Immune Drug Discov. 2015. PMID: 26556498 Review.
Metreleptin treatment has been demonstrated to improve metabolic abnormalities such as hyperglycemia, hypertriglyceridemia, increased hepatic fat content and elevated liver enzymes alanine transaminase and aspartate transaminase in patients with generalized l …
Metreleptin treatment has been demonstrated to improve metabolic abnormalities such as hyperglycemia, hypertriglyceridemia, increased hepati …
Biomarker-Based Approaches for Assessing Alcohol Use Disorders.
Niemelä O. Niemelä O. Int J Environ Res Public Health. 2016 Jan 27;13(2):166. doi: 10.3390/ijerph13020166. Int J Environ Res Public Health. 2016. PMID: 26828506 Free PMC article. Review.
Interventions should be initiated by obtaining information on the actual amounts of recent alcohol consumption through questionnaires and measurements of ethanol and its specific metabolites, such as ethyl glucuronide. Carbohydrate-deficient transferrin is a valuable tool …
Interventions should be initiated by obtaining information on the actual amounts of recent alcohol consumption through questionnaires and me …
The fatty liver and insulin resistance.
Yki-Järvinen H, Westerbacka J. Yki-Järvinen H, et al. Curr Mol Med. 2005 May;5(3):287-95. doi: 10.2174/1566524053766031. Curr Mol Med. 2005. PMID: 15892648 Review.
Liver fat content can be decreased by weight loss. In addition, treatment of both lipodystrophic and type 2 diabetic patients with PPARgamma agonists but not metformin decreases liver fat and increases adiponectin levels. Markers of liver fat such as serum alanine a …
Liver fat content can be decreased by weight loss. In addition, treatment of both lipodystrophic and type 2 diabetic patients with PP …
Molecular insights into primary hyperoxaluria type 1 pathogenesis.
Cellini B, Oppici E, Paiardini A, Montioli R. Cellini B, et al. Front Biosci (Landmark Ed). 2012 Jan 1;17(2):621-34. doi: 10.2741/3948. Front Biosci (Landmark Ed). 2012. PMID: 22201765 Free article. Review.
Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disorder of glyoxylate metabolism caused by the deficiency of liver peroxisomal alanine:glyoxylate aminotransferase (AGT), a pyridoxal 5'-phosphate (PLP)-dependent enzyme. ...
Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disorder of glyoxylate metabolism caused by the deficiency of liver …
Micronutrient supplementation in adults with HIV infection.
Visser ME, Durao S, Sinclair D, Irlam JH, Siegfried N. Visser ME, et al. Cochrane Database Syst Rev. 2017 May 18;5(5):CD003650. doi: 10.1002/14651858.CD003650.pub4. Cochrane Database Syst Rev. 2017. PMID: 28518221 Free PMC article. Review.
BACKGROUND: Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the diet may be low in essential vitamins and minerals. ...However, the trial authors reported this effect only in the trial arm that received …
BACKGROUND: Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the …
25 results