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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 1
1924 1
1930 1
1931 1
1935 4
1936 3
1937 2
1938 1
1939 4
1940 3
1941 2
1942 1
1945 4
1946 24
1947 30
1948 47
1949 42
1950 52
1951 81
1952 59
1953 64
1954 72
1955 71
1956 75
1957 92
1958 58
1959 87
1960 77
1961 67
1962 94
1963 106
1964 126
1965 125
1966 103
1967 110
1968 102
1969 92
1970 113
1971 112
1972 107
1973 119
1974 84
1975 328
1976 296
1977 275
1978 271
1979 293
1980 318
1981 483
1982 633
1983 619
1984 699
1985 734
1986 718
1987 751
1988 795
1989 850
1990 941
1991 1064
1992 1123
1993 1348
1994 1451
1995 1490
1996 1473
1997 1545
1998 1707
1999 1668
2000 1919
2001 1995
2002 1820
2003 1895
2004 2038
2005 2070
2006 2133
2007 2255
2008 2234
2009 2280
2010 2250
2011 2145
2012 2199
2013 2201
2014 2318
2015 2191
2016 2212
2017 2143
2018 2093
2019 2074
2020 2149
2021 2043
2022 1924
2023 1817
2024 641

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69,365 results

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Page 1
GABA and glutamate in the human brain.
Petroff OA. Petroff OA. Neuroscientist. 2002 Dec;8(6):562-73. doi: 10.1177/1073858402238515. Neuroscientist. 2002. PMID: 12467378 Review.
Glutamate is the metabolic precursor of GABA, which can be recycled through the tricarboxylic acid cycle to synthesize glutamate. GABA synthesis is unique among neurotransmitters, having two separate isoforms of the rate-controlling enzyme, glutamic acid deca …
Glutamate is the metabolic precursor of GABA, which can be recycled through the tricarboxylic acid cycle to synthesize glutamate. GAB …
II. Glutamine and glutamate.
Tapiero H, Mathé G, Couvreur P, Tew KD. Tapiero H, et al. Biomed Pharmacother. 2002 Nov;56(9):446-57. doi: 10.1016/s0753-3322(02)00285-8. Biomed Pharmacother. 2002. PMID: 12481981 Review.
Deamidation of glutamine via glutaminase produces glutamate a precursor of gamma-amino butyric acid, a neurotransmission inhibitor. L-Glutamic acid is a ubiquitous amino acid present in many foods either in free form or in peptides and proteins. ...Mos …
Deamidation of glutamine via glutaminase produces glutamate a precursor of gamma-amino butyric acid, a neurotransmission inhibitor. L …
Glutamate: a truly functional amino acid.
Brosnan JT, Brosnan ME. Brosnan JT, et al. Amino Acids. 2013 Sep;45(3):413-8. doi: 10.1007/s00726-012-1280-4. Epub 2012 Apr 18. Amino Acids. 2013. PMID: 22526238 Review.
Post-translational carboxylation of glutamyl residues increases their affinity for calcium and plays a major role in hemostasis. Glutamate is of fundamental importance to amino acid metabolism, yet the great bulk of dietary glutamate is catabolyzed within the intestine. .. …
Post-translational carboxylation of glutamyl residues increases their affinity for calcium and plays a major role in hemostasis. Glutamate i …
The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.
Bak LK, Schousboe A, Waagepetersen HS. Bak LK, et al. J Neurochem. 2006 Aug;98(3):641-53. doi: 10.1111/j.1471-4159.2006.03913.x. Epub 2006 Jun 19. J Neurochem. 2006. PMID: 16787421 Free article. Review.
Neurons are metabolically handicapped in the sense that they are not able to perform de novo synthesis of neurotransmitter glutamate and gamma-aminobutyric acid (GABA) from glucose. A metabolite shuttle known as the glutamate/GABA-glutamine cycle describes the release of n …
Neurons are metabolically handicapped in the sense that they are not able to perform de novo synthesis of neurotransmitter glutamate and gam …
Handling Metalloproteinases.
Fridrich S, Karmilin K, Stöcker W. Fridrich S, et al. Curr Protoc Protein Sci. 2016 Feb 2;83:21.16.1-21.16.20. doi: 10.1002/0471140864.ps2116s83. Curr Protoc Protein Sci. 2016. PMID: 26836407 Review.
Substrate cleavage by metalloproteinases involves nucleophilic attack on the scissile peptide bond by a water molecule that is polarized by a catalytic metal, usually a zinc ion, and a general base, usually the carboxyl group of a glutamic acid side chain. The zinc …
Substrate cleavage by metalloproteinases involves nucleophilic attack on the scissile peptide bond by a water molecule that is polarized by …
Glutamate: Where does it come from and where does it go?
Olsen GM, Sonnewald U. Olsen GM, et al. Neurochem Int. 2015 Sep;88:47-52. doi: 10.1016/j.neuint.2014.11.006. Epub 2014 Nov 20. Neurochem Int. 2015. PMID: 25447768
In the present study cerebellar granule neurons were incubated with medium containing 0.1, 0.25 or 0.5 mM [U-(13)C]glutamate or [U-(13)C]aspartate and pyruvate recycling in combination with tricarboxylic acid (TCA) cycle metabolism was analysed in glutamate, aspartate and …
In the present study cerebellar granule neurons were incubated with medium containing 0.1, 0.25 or 0.5 mM [U-(13)C]glutamate or [U-(13)C]asp …
Glutamic acid promotes hair growth in mice.
Jara CP, de Andrade Berti B, Mendes NF, Engel DF, Zanesco AM, Pereira de Souza GF, de Medeiros Bezerra R, de Toledo Bagatin J, Maria-Engler SS, Morari J, Velander WH, Velloso LA, Araújo EP. Jara CP, et al. Sci Rep. 2021 Jul 29;11(1):15453. doi: 10.1038/s41598-021-94816-y. Sci Rep. 2021. PMID: 34326383 Free PMC article.
Abnormal distribution of glutamic acid receptors occurs in skin hyperproliferative conditions such as psoriasis and skin regeneration; however, the biological function of glutamic acid in the skin remains unclear. ...Topical application of glutamic …
Abnormal distribution of glutamic acid receptors occurs in skin hyperproliferative conditions such as psoriasis and skin regen …
The Roles of Dietary Glutamate in the Intestine.
Tomé D. Tomé D. Ann Nutr Metab. 2018;73 Suppl 5:15-20. doi: 10.1159/000494777. Epub 2018 Dec 3. Ann Nutr Metab. 2018. PMID: 30508814 Free article. Review.
Glutamate (Glu), either as one of the amino acids of protein or in free form, constitutes up to 8-10% of amino acid content in the human diet, with an intake of about 10-20 g/day in adults. ...Glu is the most important fuel for intestinal tissue, it is involved in gut prot …
Glutamate (Glu), either as one of the amino acids of protein or in free form, constitutes up to 8-10% of amino acid content in the hu …
Glutamic acid, twenty years later.
Garattini S. Garattini S. J Nutr. 2000 Apr;130(4S Suppl):901S-9S. doi: 10.1093/jn/130.4.901S. J Nutr. 2000. PMID: 10736350 Review.
This review examines progress in understanding the physiologic functions of glutamic acid in the body since the first symposium on glutamic acid physiology and biochemistry was held at the Mario Negri Institute in Milan in 1978. The topics reviewed, al …
This review examines progress in understanding the physiologic functions of glutamic acid in the body since the first symposiu …
Associations Between Habitual Dietary Behaviors and Glutamic Acid Levels in Human Milk.
Nakai S, Tateoka Y, Miyaguchi Y, Takahashi M, Ogita H. Nakai S, et al. J Hum Lact. 2023 May;39(2):315-324. doi: 10.1177/08903344221095784. Epub 2022 Jun 4. J Hum Lact. 2023. PMID: 35658699
BACKGROUND: Glutamic acid, an amino acid that exhibits umami taste, is utilized in Japanese food and is abundant in human milk. ...There was no association between glutamic acid concentrations in human milk and plasma or between glutamic …
BACKGROUND: Glutamic acid, an amino acid that exhibits umami taste, is utilized in Japanese food and is abundant in hum …
69,365 results
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