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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1923 1
1924 2
1925 5
1926 3
1927 4
1928 1
1929 3
1930 7
1931 3
1932 5
1933 7
1934 4
1935 6
1936 5
1937 2
1938 3
1939 4
1941 2
1943 4
1945 6
1946 8
1947 18
1948 12
1949 16
1950 28
1951 50
1952 50
1953 61
1954 42
1955 45
1956 54
1957 47
1958 72
1959 62
1960 56
1961 75
1962 91
1963 151
1964 264
1965 226
1966 213
1967 226
1968 281
1969 305
1970 324
1971 333
1972 312
1973 347
1974 370
1975 441
1976 471
1977 437
1978 502
1979 562
1980 699
1981 726
1982 834
1983 944
1984 1159
1985 1143
1986 1289
1987 1354
1988 1539
1989 1602
1990 1778
1991 2019
1992 2250
1993 2436
1994 2671
1995 2960
1996 3147
1997 3257
1998 3293
1999 3371
2000 3844
2001 3968
2002 4216
2003 4558
2004 4871
2005 5397
2006 5261
2007 5397
2008 5418
2009 5625
2010 6152
2011 6539
2012 6964
2013 7270
2014 7352
2015 7316
2016 7136
2017 7251
2018 7673
2019 7992
2020 8838
2021 9062
2022 9246
2023 8674
2024 7294
2025 12

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187,683 results

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Page 1
Glutathione: overview of its protective roles, measurement, and biosynthesis.
Forman HJ, Zhang H, Rinna A. Forman HJ, et al. Mol Aspects Med. 2009 Feb-Apr;30(1-2):1-12. doi: 10.1016/j.mam.2008.08.006. Epub 2008 Aug 30. Mol Aspects Med. 2009. PMID: 18796312 Free PMC article. Review.
This review is the introduction to a special issue concerning, glutathione (GSH), the most abundant low molecular weight thiol compound synthesized in cells. ...The purpose here is to provide a brief overview of some of the important aspects of glutathione metabolis …
This review is the introduction to a special issue concerning, glutathione (GSH), the most abundant low molecular weight thiol compou …
Unraveling the Potential Role of Glutathione in Multiple Forms of Cell Death in Cancer Therapy.
Lv H, Zhen C, Liu J, Yang P, Hu L, Shang P. Lv H, et al. Oxid Med Cell Longev. 2019 Jun 10;2019:3150145. doi: 10.1155/2019/3150145. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31281572 Free PMC article. Review.
Glutathione is the principal intracellular antioxidant buffer against oxidative stress and mainly exists in the forms of reduced glutathione (GSH) and oxidized glutathione (GSSG). ...In this review, we firstly focus on glutathione homeostasis from the
Glutathione is the principal intracellular antioxidant buffer against oxidative stress and mainly exists in the forms of reduced g
Glutathione: subcellular distribution and membrane transport (1).
Oestreicher J, Morgan B. Oestreicher J, et al. Biochem Cell Biol. 2019 Jun;97(3):270-289. doi: 10.1139/bcb-2018-0189. Epub 2018 Nov 14. Biochem Cell Biol. 2019. PMID: 30427707 Review.
Whilst glutathione transport is essential for the supply and replenishment of subcellular glutathione pools, recent evidence supports a more active role for glutathione transport in the regulation of subcellular glutathione redox homeostasis. ...In thi …
Whilst glutathione transport is essential for the supply and replenishment of subcellular glutathione pools, recent evidence s …
The Glutathione Conundrum: Stoichiometric Disconnect between Its Formation and Oxidative Stress.
Boysen G. Boysen G. Chem Res Toxicol. 2017 May 15;30(5):1113-1116. doi: 10.1021/acs.chemrestox.7b00018. Epub 2017 Apr 26. Chem Res Toxicol. 2017. PMID: 28426193 Free PMC article. Review.
Glutathione (GSH) is the most abundant antioxidant and is believed to maintain redox potential in tissues, cells, and individual compartments. However, GSH concentrations in some tumor cells and tissues have been reported to be as high as 1-10 mM, a concentration that is u
Glutathione (GSH) is the most abundant antioxidant and is believed to maintain redox potential in tissues, cells, and individual comp
Glutathione, altruistic metabolite in fungi.
Pócsi I, Prade RA, Penninckx MJ. Pócsi I, et al. Adv Microb Physiol. 2004;49:1-76. doi: 10.1016/S0065-2911(04)49001-8. Adv Microb Physiol. 2004. PMID: 15518828 Review.
In addition, the response to oxidative stress also involves GSH biosynthesis enzymes, NADPH-dependent GSH-regenerating reductase, glutathione S-transferase along with peroxide-eliminating glutathione peroxidase and glutaredoxins. ...GSH S-conjugates may also form in …
In addition, the response to oxidative stress also involves GSH biosynthesis enzymes, NADPH-dependent GSH-regenerating reductase, glutath
Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy.
Meister A. Meister A. Pharmacol Ther. 1991;51(2):155-94. doi: 10.1016/0163-7258(91)90076-x. Pharmacol Ther. 1991. PMID: 1784629 Review.
This article emphasizes an approach in which the synthesis of glutathione is selectively inhibited in vivo leading to glutathione deficiency. This is achieved through use of transition-state inactivators of gamma-glutamylcysteine synthetase, the enzyme that catalyze …
This article emphasizes an approach in which the synthesis of glutathione is selectively inhibited in vivo leading to glutathione
Glutathione in defense and signaling: lessons from a small thiol.
Dickinson DA, Forman HJ. Dickinson DA, et al. Ann N Y Acad Sci. 2002 Nov;973:488-504. doi: 10.1111/j.1749-6632.2002.tb04690.x. Ann N Y Acad Sci. 2002. PMID: 12485918 Review.
The major pathways for GSH metabolism in defense of the cell are reduction of hydroperoxides by glutathione peroxidases (GSHPx) and some peroxiredoxins, which yield glutathione disulfide (GSSG), and conjugation reactions catalyzed by glutathione-S-transferase …
The major pathways for GSH metabolism in defense of the cell are reduction of hydroperoxides by glutathione peroxidases (GSHPx) and s …
Implications of glutathione-S transferase P1 in MAPK signaling as a CRAF chaperone: In memory of Dr. Irving Listowsky.
Niitsu Y, Sato Y, Takayama T. Niitsu Y, et al. Proc Jpn Acad Ser B Phys Biol Sci. 2022;98(2):72-86. doi: 10.2183/pjab.98.005. Proc Jpn Acad Ser B Phys Biol Sci. 2022. PMID: 35153270 Free PMC article. Review.
Glutathione-S transferase P1 (GSTP1) is one of the glutathione-S transferase isozymes that belong to a family of phase II metabolic isozymes. ...
Glutathione-S transferase P1 (GSTP1) is one of the glutathione-S transferase isozymes that belong to a family of phase II meta
Glutathione metabolism and its role in hepatotoxicity.
DeLeve LD, Kaplowitz N. DeLeve LD, et al. Pharmacol Ther. 1991 Dec;52(3):287-305. doi: 10.1016/0163-7258(91)90029-l. Pharmacol Ther. 1991. PMID: 1820580 Review.
Glutathione (GSH) fulfills several essential functions: Detoxification of free radicals and toxic oxygen radicals, thiol-disulfide exchange and storage and transfer of cysteine. ...Within the cell mitochondrial GSH is the main defense against physiological oxidant stress g
Glutathione (GSH) fulfills several essential functions: Detoxification of free radicals and toxic oxygen radicals, thiol-disulfide ex
187,683 results
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