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Glycine restores glutathione and protects against oxidative stress in vascular tissue from sucrose-fed rats.
Ruiz-Ramírez A, Ortiz-Balderas E, Cardozo-Saldaña G, Diaz-Diaz E, El-Hafidi M. Ruiz-Ramírez A, et al. Clin Sci (Lond). 2014 Jan 1;126(1):19-29. doi: 10.1042/CS20130164. Clin Sci (Lond). 2014. PMID: 23742196
The present study was undertaken to investigate the mechanism by which glycine, supplemented to the diet of SF (sucrose-fed) rats, modulates glutathione biosynthesis and protects against oxidative stress and altered endothelium-dependent relaxat …
The present study was undertaken to investigate the mechanism by which glycine, supplemented to the diet of SF (sucrose-fed) rats, mo …
Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, protects liver against carbon tetrachloride-induced oxidative stress in transgenic mice expressing the hepatitis C virus polyprotein.
Hidaka I, Hino K, Korenaga M, Gondo T, Nishina S, Ando M, Okuda M, Sakaida I. Hidaka I, et al. Liver Int. 2007 Aug;27(6):845-53. doi: 10.1111/j.1478-3231.2007.01492.x. Liver Int. 2007. PMID: 17617128
The aim of this study was to investigate if SNMC had an anti-oxidative effect, as oxidative stress has been proposed to be one of the mechanisms of liver injury in hepatitis C virus (HCV)-associated chronic liver diseases. ...CONCLUSIONS: Transgenic mice expr …
The aim of this study was to investigate if SNMC had an anti-oxidative effect, as oxidative stress has been proposed to …
Mitochondria protection as a mechanism underlying the hepatoprotective effects of glycine in cholestatic mice.
Heidari R, Ghanbarinejad V, Mohammadi H, Ahmadi A, Ommati MM, Abdoli N, Aghaei F, Esfandiari A, Azarpira N, Niknahad H. Heidari R, et al. Biomed Pharmacother. 2018 Jan;97:1086-1095. doi: 10.1016/j.biopha.2017.10.166. Epub 2017 Nov 10. Biomed Pharmacother. 2018. PMID: 29136945
Glycine supplementation (0.25% and 1%) decreased mitochondrial swelling, ROS, and LPO. Moreover, glycine treatment improved mitochondrial membrane potential and restored liver mitochondrial ATP. On the other hand, it was found that glycine supplementat
Glycine supplementation (0.25% and 1%) decreased mitochondrial swelling, ROS, and LPO. Moreover, glycine treatment improved mi
Glycine increases glyoxalase-1 function by promoting nuclear factor erythroid 2-related factor 2 translocation into the nucleus of kidney cells of streptozotocin-induced diabetic rats.
Wang Z, Zhao D, Chen L, Li J, Yuan G, Yang G, Zhang H, Guo X, Zhang J. Wang Z, et al. J Diabetes Investig. 2019 Sep;10(5):1189-1198. doi: 10.1111/jdi.13032. Epub 2019 Mar 28. J Diabetes Investig. 2019. PMID: 30825261 Free PMC article.
AIMS/INTRODUCTION: We have previously reported that glycine suppresses the advanced glycation end-products signaling pathway and mitigates subsequent oxidative stress in the kidneys of diabetic rats. ...CONCLUSIONS: The present study shows that glycine
AIMS/INTRODUCTION: We have previously reported that glycine suppresses the advanced glycation end-products signaling pathway and miti …
Alterations of bronchial epithelial metabolome by cigarette smoke are reversible by an antioxidant, O-methyl-L-tyrosinyl-γ-L-glutamyl-L-cysteinylglycine.
Aug A, Altraja A, Altraja S, Laaniste L, Mahlapuu R, Soomets U, Kilk K. Aug A, et al. Am J Respir Cell Mol Biol. 2014 Oct;51(4):586-94. doi: 10.1165/rcmb.2013-0377OC. Am J Respir Cell Mol Biol. 2014. PMID: 24810251
This study was designed to determine the dynamics of metabolome changes in HBECs treated with cigarette smoke condensate (CSC), and to test whether normal metabolism can be restored by synthetic antioxidants. ...Subsequent restoration of their content by UPF1 suppor …
This study was designed to determine the dynamics of metabolome changes in HBECs treated with cigarette smoke condensate (CSC), and to test …
Differential cytoprotection by glycine against oxidant damage to proximal tubule cells.
Sogabe K, Roeser NF, Venkatachalam MA, Weinberg JM. Sogabe K, et al. Kidney Int. 1996 Sep;50(3):845-54. doi: 10.1038/ki.1996.384. Kidney Int. 1996. PMID: 8872959 Free article.
Glycine did not the alter changes in cytoskeletal proteins, thiols, or TBARS produced by any of the agents. Protection against tBHP toxicity by deferoxamine and DPPD was accompanied by substantial suppression of TBARS accumulation. ...Extensive oxidative
Glycine did not the alter changes in cytoskeletal proteins, thiols, or TBARS produced by any of the agents. Protection
Activation of Group II/III metabotropic glutamate receptors attenuates LPS-induced astroglial neurotoxicity via promoting glutamate uptake.
Zhou F, Yao HH, Wu JY, Yang YJ, Ding JH, Zhang J, Hu G. Zhou F, et al. J Neurosci Res. 2006 Aug 1;84(2):268-77. doi: 10.1002/jnr.20897. J Neurosci Res. 2006. PMID: 16752416
Altered glial function that leads to oxidative stress and excitotoxicity may contribute to the initiation or progression of neuronal death in neurodegenerative diseases. ...Furthermore, we found that the repression of astroglial uptake function could be revived by G …
Altered glial function that leads to oxidative stress and excitotoxicity may contribute to the initiation or progression of ne …
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