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Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.
Landau DA, Clement K, Ziller MJ, Boyle P, Fan J, Gu H, Stevenson K, Sougnez C, Wang L, Li S, Kotliar D, Zhang W, Ghandi M, Garraway L, Fernandes SM, Livak KJ, Gabriel S, Gnirke A, Lander ES, Brown JR, Neuberg D, Kharchenko PV, Hacohen N, Getz G, Meissner A, Wu CJ. Landau DA, et al. Among authors: gnirke a. Cancer Cell. 2014 Dec 8;26(6):813-825. doi: 10.1016/j.ccell.2014.10.012. Cancer Cell. 2014. PMID: 25490447 Free PMC article.
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.
Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, Guttman M, Epstein C, Park H, Kohlbacher O, Rinn J, Gnirke A, Lander ES, Bernstein BE, Meissner A. Gifford CA, et al. Among authors: gnirke a. Cell. 2013 May 23;153(5):1149-63. doi: 10.1016/j.cell.2013.04.037. Epub 2013 May 9. Cell. 2013. PMID: 23664763 Free PMC article.
Targeted bisulfite sequencing of the dynamic DNA methylome.
Ziller MJ, Stamenova EK, Gu H, Gnirke A, Meissner A. Ziller MJ, et al. Among authors: gnirke a. Epigenetics Chromatin. 2016 Dec 3;9:55. doi: 10.1186/s13072-016-0105-1. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27980681 Free PMC article.
Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.
Kretzmer H, Biran A, Purroy N, Lemvigh CK, Clement K, Gruber M, Gu H, Rassenti L, Mohammad AW, Lesnick C, Slager SL, Braggio E, Shanafelt TD, Kay NE, Fernandes SM, Brown JR, Wang L, Li S, Livak KJ, Neuberg DS, Klages S, Timmermann B, Kipps TJ, Campo E, Gnirke A, Wu CJ, Meissner A. Kretzmer H, et al. Among authors: gnirke a. Blood Cancer Discov. 2021 Jan;2(1):54-69. doi: 10.1158/2643-3230.BCD-19-0058. Epub 2020 Dec 3. Blood Cancer Discov. 2021. PMID: 33604581 Free PMC article.
Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
Biran A, Yin S, Kretzmer H, Ten Hacken E, Parvin S, Lucas F, Uduman M, Gutierrez C, Dangle N, Billington L, Regis FF, Rassenti LZ, Mohammad A, Hoffmann GB, Stevenson K, Zheng M, Witten E, Fernandes SM, Tausch E, Sun C, Stilgenbauer S, Brown JR, Kipps TJ, Aster JC, Gnirke A, Neuberg DS, Letai A, Wang L, Carrasco RD, Meissner A, Wu CJ. Biran A, et al. Among authors: gnirke a. Cancer Res. 2021 Dec 15;81(24):6117-6130. doi: 10.1158/0008-5472.CAN-21-1273. Epub 2021 Oct 22. Cancer Res. 2021. PMID: 34686499 Free PMC article.
Genome-scale DNA methylation maps of pluripotent and differentiated cells.
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Meissner A, et al. Among authors: gnirke a. Nature. 2008 Aug 7;454(7205):766-70. doi: 10.1038/nature07107. Epub 2008 Jul 6. Nature. 2008. PMID: 18600261 Free PMC article.
High-throughput bisulfite sequencing in mammalian genomes.
Smith ZD, Gu H, Bock C, Gnirke A, Meissner A. Smith ZD, et al. Among authors: gnirke a. Methods. 2009 Jul;48(3):226-32. doi: 10.1016/j.ymeth.2009.05.003. Epub 2009 May 12. Methods. 2009. PMID: 19442738 Free PMC article.
122 results