Godbehere S - Search Results

1

Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor.

Seregin SS, Hartman ZC, Appledorn DM, Godbehere S, Jiang H, Frank MM, Amalfitano A. Seregin SS, et al. Among authors: godbehere s. J Innate Immun. 2010;2(4):353-9. doi: 10.1159/000284368. Epub 2010 Feb 11. J Innate Immun. 2010. PMID: 20375551 Free PMC article.

2

CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies.

Seregin SS, Aldhamen YA, Appledorn DM, Schuldt NJ, McBride AJ, Bujold M, Godbehere SS, Amalfitano A. Seregin SS, et al. Among authors: godbehere ss. Gene Ther. 2009 Oct;16(10):1245-59. doi: 10.1038/gt.2009.77. Epub 2009 Jun 25. Gene Ther. 2009. PMID: 19554032 Free PMC article.

3

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo.

Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, Parameswaran N, Amalfitano A. Appledorn DM, et al. Among authors: godbehere s. J Immunol. 2008 Aug 1;181(3):2134-44. doi: 10.4049/jimmunol.181.3.2134. J Immunol. 2008. PMID: 18641352

4

Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy.

Seregin SS, Appledorn DM, McBride AJ, Schuldt NJ, Aldhamen YA, Voss T, Wei J, Bujold M, Nance W, Godbehere S, Amalfitano A. Seregin SS, et al. Among authors: godbehere s. Mol Ther. 2009 Apr;17(4):685-96. doi: 10.1038/mt.2008.297. Epub 2009 Jan 27. Mol Ther. 2009. PMID: 19174760 Free PMC article.

5

Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo.

Seregin SS, Aldhamen YA, Appledorn DM, Hartman ZC, Schuldt NJ, Scott J, Godbehere S, Jiang H, Frank MM, Amalfitano A. Seregin SS, et al. Among authors: godbehere s. Blood. 2010 Sep 9;116(10):1669-77. doi: 10.1182/blood-2010-03-276949. Epub 2010 May 28. Blood. 2010. PMID: 20511542 Free PMC article.

6

Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and systemic cell-mediated responses against HIV antigens despite preexisting Ad5 immunity.

Appledorn DM, Aldhamen YA, Godbehere S, Seregin SS, Amalfitano A. Appledorn DM, et al. Among authors: godbehere s. Clin Vaccine Immunol. 2011 Jan;18(1):150-60. doi: 10.1128/CVI.00341-10. Epub 2010 Nov 17. Clin Vaccine Immunol. 2011. PMID: 21084461 Free PMC article.

7

Use of DAF-displaying adenovirus vectors reduces induction of transgene- and vector-specific adaptive immune responses in mice.

Seregin SS, Aldhamen YA, Appledorn DM, Zehnder J, Voss T, Godbehere S, Amalfitano A. Seregin SS, et al. Among authors: godbehere s. Hum Gene Ther. 2011 Sep;22(9):1083-94. doi: 10.1089/hum.2010.218. Epub 2011 Apr 18. Hum Gene Ther. 2011. PMID: 21388344 Free PMC article.

8

Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells.

Aldhamen YA, Pepelyayeva Y, Rastall DP, Seregin SS, Zervoudi E, Koumantou D, Aylsworth CF, Quiroga D, Godbehere S, Georgiadis D, Stratikos E, Amalfitano A. Aldhamen YA, et al. Among authors: godbehere s. J Innate Immun. 2015;7(3):275-89. doi: 10.1159/000368899. Epub 2015 Jan 14. J Innate Immun. 2015. PMID: 25591727 Free PMC article.

9

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors.

Appledorn DM, McBride A, Seregin S, Scott JM, Schuldt N, Kiang A, Godbehere S, Amalfitano A. Appledorn DM, et al. Among authors: godbehere s. Gene Ther. 2008 Dec;15(24):1606-17. doi: 10.1038/gt.2008.114. Epub 2008 Jul 10. Gene Ther. 2008. PMID: 18615115

10

beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.

Seregin SS, Appledorn DM, Patial S, Bujold M, Nance W, Godbehere S, Parameswaran N, Amalfitano A. Seregin SS, et al. Among authors: godbehere s. Virus Res. 2010 Jan;147(1):123-34. doi: 10.1016/j.virusres.2009.10.023. Epub 2009 Nov 6. Virus Res. 2010. PMID: 19896992 Free PMC article.

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